Title |
Establishment of a small animal tumour model for in vivo studies with low energy laser accelerated particles
|
---|---|
Published in |
Radiation Oncology, February 2014
|
DOI | 10.1186/1748-717x-9-57 |
Pubmed ID | |
Authors |
Kerstin Brüchner, Elke Beyreuther, Michael Baumann, Mechthild Krause, Melanie Oppelt, Jörg Pawelke |
Abstract |
The long-term aim of developing a laser based acceleration of protons and ions towards clinical application requires not only substantial technological progress, but also the radiobiological characterization of the resulting ultra-short pulsed particle beams. Recent in vitro data showed similar effects of laser-accelerated versus "conventional" protons on clonogenic cell survival. As the proton energies currently achieved by laser driven acceleration are too low to penetrate standard tumour models on mouse legs, the aim of the present work was to establish a tumour model allowing for the penetration of low energy protons (~ 20 MeV) to further verify their effects in vivo. |
X Demographics
Geographical breakdown
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United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
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Unknown | 37 | 100% |
Demographic breakdown
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Student > Ph. D. Student | 8 | 22% |
Researcher | 6 | 16% |
Professor > Associate Professor | 4 | 11% |
Student > Doctoral Student | 3 | 8% |
Student > Master | 3 | 8% |
Other | 6 | 16% |
Unknown | 7 | 19% |
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Computer Science | 1 | 3% |
Other | 3 | 8% |
Unknown | 10 | 27% |