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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The role of 5-HT receptors in depression
|
|---|---|
| Published in |
Molecular Brain, June 2017
|
| DOI | 10.1186/s13041-017-0306-y |
| Pubmed ID | |
| Authors |
Christine N. Yohn, Mark M. Gergues, Benjamin Adam Samuels |
| Abstract |
Depression is a polygenic and highly complex psychiatric disorder that remains a major burden on society. Antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), are some of the most commonly prescribed drugs worldwide. In this review, we will discuss the evidence that links serotonin and serotonin receptors to the etiology of depression and the mechanisms underlying response to antidepressant treatment. We will then revisit the role of serotonin in three distinct hypotheses that have been proposed over the last several decades to explain the pathophysiology of depression: the monoamine, neurotrophic, and neurogenic hypotheses. Finally, we will discuss how recent studies into serotonin receptors have implicated specific neural circuitry in mediating the antidepressant response, with a focus being placed on the hippocampus. |
X Demographics
The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 4 | 44% |
| United States | 3 | 33% |
| Colombia | 1 | 11% |
| Unknown | 1 | 11% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 67% |
| Practitioners (doctors, other healthcare professionals) | 1 | 11% |
| Science communicators (journalists, bloggers, editors) | 1 | 11% |
| Scientists | 1 | 11% |
Mendeley readers
The data shown below were compiled from readership statistics for 680 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 680 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 147 | 22% |
| Student > Master | 110 | 16% |
| Student > Ph. D. Student | 72 | 11% |
| Researcher | 60 | 9% |
| Other | 28 | 4% |
| Other | 71 | 10% |
| Unknown | 192 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 112 | 16% |
| Biochemistry, Genetics and Molecular Biology | 90 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 64 | 9% |
| Medicine and Dentistry | 59 | 9% |
| Agricultural and Biological Sciences | 43 | 6% |
| Other | 100 | 15% |
| Unknown | 212 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 146. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 November 2023.
All research outputs
#272,879
of 24,799,506 outputs
Outputs from Molecular Brain
#3
of 1,184 outputs
Outputs of similar age
#5,967
of 321,131 outputs
Outputs of similar age from Molecular Brain
#1
of 20 outputs
Altmetric has tracked 24,799,506 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,184 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 321,131 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.