Title |
Whole genome sequencing of Ethiopian highlanders reveals conserved hypoxia tolerance genes
|
---|---|
Published in |
Genome Biology, February 2014
|
DOI | 10.1186/gb-2014-15-2-r36 |
Pubmed ID | |
Authors |
Nitin Udpa, Roy Ronen, Dan Zhou, Junbin Liang, Tsering Stobdan, Otto Appenzeller, Ye Yin, Yuanping Du, Lixia Guo, Rui Cao, Yu Wang, Xin Jin, Chen Huang, Wenlong Jia, Dandan Cao, Guangwu Guo, Victoria E Claydon, Roger Hainsworth, Jorge L Gamboa, Mehila Zibenigus, Guta Zenebe, Jin Xue, Siqi Liu, Kelly A Frazer, Yingrui Li, Vineet Bafna, Gabriel G Haddad |
Abstract |
Although it has long been proposed that genetic factors contribute to adaptation to high altitude, such factors remain largely unverified. Recent advances in high-throughput sequencing have made it feasible to analyze genome-wide patterns of genetic variation in human populations. Since traditionally such studies surveyed only a small fraction of the genome, interpretation of the results was limited. |
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Mexico | 2 | 4% |
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Sweden | 1 | 2% |
Germany | 1 | 2% |
India | 1 | 2% |
Other | 3 | 6% |
Unknown | 17 | 34% |
Demographic breakdown
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Members of the public | 20 | 40% |
Practitioners (doctors, other healthcare professionals) | 2 | 4% |
Science communicators (journalists, bloggers, editors) | 1 | 2% |
Mendeley readers
Geographical breakdown
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United States | 3 | 3% |
Chile | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 99 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 26 | 25% |
Researcher | 15 | 14% |
Student > Bachelor | 11 | 11% |
Professor | 8 | 8% |
Professor > Associate Professor | 7 | 7% |
Other | 21 | 20% |
Unknown | 16 | 15% |
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Biochemistry, Genetics and Molecular Biology | 18 | 17% |
Medicine and Dentistry | 7 | 7% |
Computer Science | 4 | 4% |
Engineering | 3 | 3% |
Other | 9 | 9% |
Unknown | 23 | 22% |