Title |
Whole genome sequencing in Drosophila virilis identifies Polyphemus, a recently activated Tc1-like transposon with a possible role in hybrid dysgenesis
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Published in |
Mobile DNA, February 2014
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DOI | 10.1186/1759-8753-5-6 |
Pubmed ID | |
Authors |
Justin P Blumenstiel |
Abstract |
Hybrid dysgenic syndromes in Drosophila have been critical for characterizing host mechanisms of transposable element (TE) regulation. This is because a common feature of hybrid dysgenesis is germline TE mobilization that occurs when paternally inherited TEs are not matched with a maternal pool of silencing RNAs that maintain transgenerational TE control. In the face of this imbalance TEs become activated in the germline and can cause F1 sterility. The syndrome of hybrid dysgenesis in Drosophila virilis was the first to show that the mobilization of one dominant TE, the Penelope retrotransposon, may lead to the mobilization of other unrelated elements. However, it is not known how many different elements contribute and no exhaustive search has been performed to identify additional ones. To identify additional TEs that may contribute to hybrid dysgenesis in Drosophila virilis, I analyzed repeat content in genome sequences of inducer and non-inducer lines. |
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Mendeley readers
Geographical breakdown
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Brazil | 2 | 13% |
Canada | 1 | 6% |
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Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 4 | 25% |
Professor > Associate Professor | 2 | 13% |
Student > Bachelor | 1 | 6% |
Student > Ph. D. Student | 1 | 6% |
Other | 1 | 6% |
Unknown | 1 | 6% |
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Medicine and Dentistry | 1 | 6% |
Other | 1 | 6% |
Unknown | 2 | 13% |