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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Engineering CAR-T cells
|
|---|---|
| Published in |
Biomarker Research, June 2017
|
| DOI | 10.1186/s40364-017-0102-y |
| Pubmed ID | |
| Authors |
Cheng Zhang, Jun Liu, Jiang F. Zhong, Xi Zhang |
| Abstract |
Chimeric antigen receptor redirected T cells (CAR-T cells) have achieved inspiring outcomes in patients with B cell malignancies, and are now being investigated in other hematologic malignancies and solid tumors. CAR-T cells are generated by the T cells from patients' or donors' blood. After the T cells are expanded and genetically modified, they are reinfused into the patients. However, many challenges still need to be resolved in order for this technology to gain widespread adoption. In this review, we first discuss the structure and evolution of chimeric antigen receptors. We then report on the tools used for production of CAR-T cells. Finally, we address the challenges posed by CAR-T cells. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 1,304 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1304 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 262 | 20% |
| Student > Master | 159 | 12% |
| Researcher | 115 | 9% |
| Student > Ph. D. Student | 110 | 8% |
| Student > Doctoral Student | 50 | 4% |
| Other | 109 | 8% |
| Unknown | 499 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 313 | 24% |
| Immunology and Microbiology | 111 | 9% |
| Medicine and Dentistry | 99 | 8% |
| Agricultural and Biological Sciences | 74 | 6% |
| Engineering | 43 | 3% |
| Other | 127 | 10% |
| Unknown | 537 | 41% |
Attention Score in Context
This research output has an Altmetric Attention Score of 38. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 January 2024.
All research outputs
#978,836
of 23,818,521 outputs
Outputs from Biomarker Research
#6
of 350 outputs
Outputs of similar age
#21,234
of 317,318 outputs
Outputs of similar age from Biomarker Research
#1
of 5 outputs
Altmetric has tracked 23,818,521 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 350 research outputs from this source. They receive a mean Attention Score of 4.5. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 317,318 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them