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Single-base resolution of mouse offspring brain methylome reveals epigenome modifications caused by gestational folic acid

Overview of attention for article published in Epigenetics & Chromatin, February 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)

Mentioned by

blogs
1 blog
twitter
1 tweeter
reddit
1 Redditor

Citations

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54 Dimensions

Readers on

mendeley
85 Mendeley
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Title
Single-base resolution of mouse offspring brain methylome reveals epigenome modifications caused by gestational folic acid
Published in
Epigenetics & Chromatin, February 2014
DOI 10.1186/1756-8935-7-3
Pubmed ID
Authors

Subit Barua, Salomon Kuizon, Kathryn K Chadman, Michael J Flory, W Ted Brown, Mohammed A Junaid

Abstract

Epigenetic modifications, such as cytosine methylation in CpG-rich regions, regulate multiple functions in mammalian development. Maternal nutrients affecting one-carbon metabolism during gestation can exert long-term effects on the health of the progeny. Using C57BL/6 J mice, we investigated whether the amount of ingested maternal folic acid (FA) during gestation impacted DNA methylation in the offspring's cerebral hemispheres. Reduced representation bisulfite sequencing at single-base resolution was performed to analyze genome-wide DNA methylation profiles.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
India 1 1%
Brazil 1 1%
China 1 1%
Canada 1 1%
Unknown 79 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 21 25%
Researcher 16 19%
Student > Master 12 14%
Student > Bachelor 10 12%
Student > Doctoral Student 5 6%
Other 13 15%
Unknown 8 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 32 38%
Biochemistry, Genetics and Molecular Biology 19 22%
Medicine and Dentistry 10 12%
Neuroscience 4 5%
Psychology 3 4%
Other 7 8%
Unknown 10 12%

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2017.
All research outputs
#3,666,147
of 21,363,193 outputs
Outputs from Epigenetics & Chromatin
#152
of 547 outputs
Outputs of similar age
#36,191
of 201,751 outputs
Outputs of similar age from Epigenetics & Chromatin
#1
of 1 outputs
Altmetric has tracked 21,363,193 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 547 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 201,751 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them