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Single-base resolution of mouse offspring brain methylome reveals epigenome modifications caused by gestational folic acid

Overview of attention for article published in Epigenetics & Chromatin, February 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#46 of 459)
  • High Attention Score compared to outputs of the same age (90th percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
2 tweeters
reddit
1 Redditor

Citations

dimensions_citation
51 Dimensions

Readers on

mendeley
83 Mendeley
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Title
Single-base resolution of mouse offspring brain methylome reveals epigenome modifications caused by gestational folic acid
Published in
Epigenetics & Chromatin, February 2014
DOI 10.1186/1756-8935-7-3
Pubmed ID
Authors

Subit Barua, Salomon Kuizon, Kathryn K Chadman, Michael J Flory, W Ted Brown, Mohammed A Junaid

Abstract

Epigenetic modifications, such as cytosine methylation in CpG-rich regions, regulate multiple functions in mammalian development. Maternal nutrients affecting one-carbon metabolism during gestation can exert long-term effects on the health of the progeny. Using C57BL/6 J mice, we investigated whether the amount of ingested maternal folic acid (FA) during gestation impacted DNA methylation in the offspring's cerebral hemispheres. Reduced representation bisulfite sequencing at single-base resolution was performed to analyze genome-wide DNA methylation profiles.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
Canada 1 1%
India 1 1%
China 1 1%
Brazil 1 1%
Unknown 77 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 22 27%
Researcher 16 19%
Student > Master 12 14%
Student > Bachelor 10 12%
Student > Doctoral Student 5 6%
Other 13 16%
Unknown 5 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 32 39%
Biochemistry, Genetics and Molecular Biology 19 23%
Medicine and Dentistry 10 12%
Neuroscience 5 6%
Psychology 3 4%
Other 8 10%
Unknown 6 7%

Attention Score in Context

This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2017.
All research outputs
#1,307,224
of 15,922,434 outputs
Outputs from Epigenetics & Chromatin
#46
of 459 outputs
Outputs of similar age
#17,916
of 190,301 outputs
Outputs of similar age from Epigenetics & Chromatin
#1
of 1 outputs
Altmetric has tracked 15,922,434 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 459 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 190,301 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them