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X Demographics
Mendeley readers
Attention Score in Context
Title |
High throughput synthetic lethality screen reveals a tumorigenic role of adenylate cyclase in fumarate hydratase-deficient cancer cells
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Published in |
BMC Genomics, February 2014
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DOI | 10.1186/1471-2164-15-158 |
Pubmed ID | |
Authors |
Michael Boettcher, Andrew Lawson, Viola Ladenburger, Johannes Fredebohm, Jonas Wolf, Jörg D Hoheisel, Christian Frezza, Tomer Shlomi |
Abstract |
Synthetic lethality is an appealing technique for selectively targeting cancer cells which have acquired molecular changes that distinguish them from normal cells. High-throughput RNAi-based screens have been successfully used to identify synthetic lethal pathways with well-characterized tumor suppressors and oncogenes. The recent identification of metabolic tumor suppressors suggests that the concept of synthetic lethality can be applied to selectively target cancer metabolism as well. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
France | 1 | 33% |
Ireland | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 2 | 67% |
Members of the public | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 3% |
Iran, Islamic Republic of | 1 | 2% |
Germany | 1 | 2% |
Unknown | 62 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 20 | 30% |
Student > Ph. D. Student | 11 | 17% |
Student > Master | 5 | 8% |
Professor > Associate Professor | 4 | 6% |
Other | 3 | 5% |
Other | 9 | 14% |
Unknown | 14 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 31 | 47% |
Biochemistry, Genetics and Molecular Biology | 12 | 18% |
Medicine and Dentistry | 6 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
Economics, Econometrics and Finance | 1 | 2% |
Other | 1 | 2% |
Unknown | 14 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 February 2014.
All research outputs
#14,775,080
of 22,745,803 outputs
Outputs from BMC Genomics
#6,123
of 10,634 outputs
Outputs of similar age
#125,725
of 220,969 outputs
Outputs of similar age from BMC Genomics
#79
of 154 outputs
Altmetric has tracked 22,745,803 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,634 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 220,969 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 154 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.