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Genomic variability in Mexican chicken population using copy number variants

Overview of attention for article published in BMC Genomic Data, July 2017
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Title
Genomic variability in Mexican chicken population using copy number variants
Published in
BMC Genomic Data, July 2017
DOI 10.1186/s12863-017-0524-4
Pubmed ID
Authors

E. Gorla, M. C. Cozzi, S. I. Román-Ponce, F. J. Ruiz López, V. E. Vega-Murillo, S. Cerolini, A. Bagnato, M. G. Strillacci

Abstract

Copy number variations are genome polymorphism that influence phenotypic variation and are an important source of genetic variation in populations. The aim of this study was to investigate genetic variability in the Mexican Creole chicken population using CNVs. The Hidden Markov Model of the PennCNV software detected a total of 1924 CNVs in the genome of the 256 samples processed with Axiom® Genome-Wide Chicken Genotyping Array (Affymetrix). The mapped CNVs comprised 1538 gains and 386 losses, resulting at population level in 1216 CNV regions (CNVRs), of which 959 gains, 226 losses and 31 complex (i.e. containing both losses and gains). The CNVRs covered a total of 47 Mb of the whole genome sequence length, corresponding to 5.12% of the chicken galGal4 autosome assembly. This study allowed a deep insight into the structural variation in the genome of unselected Mexican chicken population, which up to now has not been genetically characterized. The genomic study disclosed that the population, even if presenting extreme morphological variation, cannot be organized in differentiated genetic subpopulations. Finally this study provides a chicken CNV map based on the 600 K SNP chip array jointly with a genome-wide gene copy number estimates in a native unselected for more than 500 years chicken population.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 32 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 25%
Student > Ph. D. Student 7 22%
Student > Master 5 16%
Other 3 9%
Professor > Associate Professor 2 6%
Other 4 13%
Unknown 3 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 59%
Biochemistry, Genetics and Molecular Biology 3 9%
Veterinary Science and Veterinary Medicine 3 9%
Computer Science 2 6%
Economics, Econometrics and Finance 1 3%
Other 0 0%
Unknown 4 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 July 2017.
All research outputs
#22,764,772
of 25,382,440 outputs
Outputs from BMC Genomic Data
#1,008
of 1,204 outputs
Outputs of similar age
#285,559
of 326,157 outputs
Outputs of similar age from BMC Genomic Data
#20
of 26 outputs
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We're also able to compare this research output to 26 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.