@nmoore07 How about double beta lactam. Meropenem 6g/day and Ertapenem 1g before meropenem with amikacin/colistin. https://t.co/aVA2cvGHOc
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Take back control by increasing the effective drug concentration. Why not. But note this was in Italy where OXA-48 like enzymes are dominant and are poor carbapenemases. May well be different in KPC or NDM dominant areas of the world.
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RT @AntibioticResis: Double carbapenem as a rescue strategy for the treatment of severe carbapenemase-producing Klebsiella pneumoniae infec…
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RT @AntibioticResis: Double carbapenem as a rescue strategy for the treatment of severe carbapenemase-producing Klebsiella pneumoniae infec…