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A short-term treatment with tumor necrosis factor-alpha enhances stem cell phenotype of human dental pulp cells

Overview of attention for article published in Stem Cell Research & Therapy, February 2014
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Title
A short-term treatment with tumor necrosis factor-alpha enhances stem cell phenotype of human dental pulp cells
Published in
Stem Cell Research & Therapy, February 2014
DOI 10.1186/scrt420
Pubmed ID
Authors

Mayu Ueda, Takuo Fujisawa, Mitsuaki Ono, Emilio Satoshi Hara, Hai Thanh Pham, Ryu Nakajima, Wataru Sonoyama, Takuo Kuboki

Abstract

During normal pulp tissue healing, inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-alpha) or interleukins, act in the initial 48 h (inflammatory phase) and play important roles not only as chemo-attractants of inflammatory cells and stem/progenitor cells, but also in inducing a cascade of reactions toward tissue regeneration and/or reparative dentin formation. Previous reports have shown that inflammatory cytokines regulate the differentiation capacity of dental pulp stem/progenitor cells (DPCs), but none has interrogated the impact of these cytokines on the stem cell phenotype of stem/progenitor cells. This study investigated the effects of a short-term treatment with TNF-alpha on the stem cell phenotype and differentiation ability of human DPCs.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 2%
India 1 2%
Unknown 62 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 16%
Student > Bachelor 9 14%
Student > Ph. D. Student 9 14%
Student > Doctoral Student 7 11%
Student > Master 6 9%
Other 8 13%
Unknown 15 23%
Readers by discipline Count As %
Medicine and Dentistry 25 39%
Agricultural and Biological Sciences 9 14%
Biochemistry, Genetics and Molecular Biology 4 6%
Nursing and Health Professions 1 2%
Veterinary Science and Veterinary Medicine 1 2%
Other 5 8%
Unknown 19 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 March 2014.
All research outputs
#18,365,132
of 22,745,803 outputs
Outputs from Stem Cell Research & Therapy
#1,721
of 2,414 outputs
Outputs of similar age
#160,763
of 221,024 outputs
Outputs of similar age from Stem Cell Research & Therapy
#26
of 31 outputs
Altmetric has tracked 22,745,803 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,414 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 221,024 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.