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A short-term treatment with tumor necrosis factor-alpha enhances stem cell phenotype of human dental pulp cells

Overview of attention for article published in Stem Cell Research & Therapy, February 2014
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1 tweeter

Citations

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40 Dimensions

Readers on

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52 Mendeley
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Title
A short-term treatment with tumor necrosis factor-alpha enhances stem cell phenotype of human dental pulp cells
Published in
Stem Cell Research & Therapy, February 2014
DOI 10.1186/scrt420
Pubmed ID
Authors

Mayu Ueda, Takuo Fujisawa, Mitsuaki Ono, Emilio Satoshi Hara, Hai Thanh Pham, Ryu Nakajima, Wataru Sonoyama, Takuo Kuboki

Abstract

During normal pulp tissue healing, inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-alpha) or interleukins, act in the initial 48 h (inflammatory phase) and play important roles not only as chemo-attractants of inflammatory cells and stem/progenitor cells, but also in inducing a cascade of reactions toward tissue regeneration and/or reparative dentin formation. Previous reports have shown that inflammatory cytokines regulate the differentiation capacity of dental pulp stem/progenitor cells (DPCs), but none has interrogated the impact of these cytokines on the stem cell phenotype of stem/progenitor cells. This study investigated the effects of a short-term treatment with TNF-alpha on the stem cell phenotype and differentiation ability of human DPCs.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 2 4%
Japan 1 2%
Unknown 49 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 19%
Student > Bachelor 9 17%
Student > Ph. D. Student 7 13%
Student > Doctoral Student 5 10%
Student > Master 5 10%
Other 9 17%
Unknown 7 13%
Readers by discipline Count As %
Medicine and Dentistry 21 40%
Agricultural and Biological Sciences 10 19%
Biochemistry, Genetics and Molecular Biology 4 8%
Veterinary Science and Veterinary Medicine 1 2%
Unspecified 1 2%
Other 5 10%
Unknown 10 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 March 2014.
All research outputs
#11,591,017
of 14,629,909 outputs
Outputs from Stem Cell Research & Therapy
#982
of 1,354 outputs
Outputs of similar age
#128,481
of 188,141 outputs
Outputs of similar age from Stem Cell Research & Therapy
#21
of 24 outputs
Altmetric has tracked 14,629,909 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,354 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 188,141 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.