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Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain

Overview of attention for article published in Genome Biology, March 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (60th percentile)

Mentioned by

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18 X users
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3 patents
googleplus
2 Google+ users

Citations

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233 Dimensions

Readers on

mendeley
292 Mendeley
citeulike
3 CiteULike
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Title
Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain
Published in
Genome Biology, March 2014
DOI 10.1186/gb-2014-15-3-r49
Pubmed ID
Authors

Lu Wen, Xianlong Li, Liying Yan, Yuexi Tan, Rong Li, Yangyu Zhao, Yan Wang, Jingcheng Xie, Yan Zhang, Chunxiao Song, Miao Yu, Xiaomeng Liu, Ping Zhu, Xiaoyu Li, Yu Hou, Hongshan Guo, Xinglong Wu, Chuan He, Ruiqiang Li, Fuchou Tang, Jie Qiao

Abstract

5-methylcytosine (mC) can be oxidized by the tet methylcytosine dioxygenase (Tet) family of enzymes to 5-hydroxymethylcytosine (hmC), which is an intermediate of mC demethylation and may also be a stable epigenetic modification that influences chromatin structure. hmC is particularly abundant in mammalian brains but its function is currently unknown. A high-resolution hydroxymethylome map is required to fully understand the function of hmC in the human brain.

X Demographics

X Demographics

The data shown below were collected from the profiles of 18 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 292 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 1%
United Kingdom 2 <1%
Japan 2 <1%
Lithuania 1 <1%
Belgium 1 <1%
Germany 1 <1%
Mexico 1 <1%
China 1 <1%
Unknown 279 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 81 28%
Researcher 58 20%
Student > Master 23 8%
Student > Bachelor 21 7%
Student > Doctoral Student 20 7%
Other 50 17%
Unknown 39 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 113 39%
Biochemistry, Genetics and Molecular Biology 70 24%
Chemistry 15 5%
Medicine and Dentistry 15 5%
Neuroscience 13 4%
Other 14 5%
Unknown 52 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 January 2024.
All research outputs
#1,711,720
of 25,374,647 outputs
Outputs from Genome Biology
#1,400
of 4,467 outputs
Outputs of similar age
#16,967
of 236,023 outputs
Outputs of similar age from Genome Biology
#26
of 65 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 236,023 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 65 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.