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Liver myofibroblasts up-regulate monocyte CD163 expression via PGE2 during hepatitis B induced liver failure

Overview of attention for article published in Journal of Translational Medicine, March 2014
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Title
Liver myofibroblasts up-regulate monocyte CD163 expression via PGE2 during hepatitis B induced liver failure
Published in
Journal of Translational Medicine, March 2014
DOI 10.1186/1479-5876-12-60
Pubmed ID
Authors

Min Zhang, Yinong Ye, Fenglan Wang, Jianyun Zhu, Qiyi Zhao, Yubao Zheng, Yurong Gu, Chan Xie, Zhanlian Huang, Qiang Tai, Yutian Chong, Zhiliang Gao

Abstract

Although patients with liver failure exhibit a generalized inflammatory-imbalance status, substantial evidence indicates that this immunosuppressive or anti-inflammatory state may be deleterious. Increased expression of CD163 (known to be involved in several anti-inflammatory functions of the immune system) in patients with liver failure is significantly correlated with a fatal outcome. However, little is known of the regulatory mechanisms that influence the expression of CD163.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 5%
Unknown 20 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 14%
Professor > Associate Professor 3 14%
Professor 2 10%
Student > Postgraduate 2 10%
Student > Ph. D. Student 2 10%
Other 4 19%
Unknown 5 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 4 19%
Medicine and Dentistry 3 14%
Biochemistry, Genetics and Molecular Biology 1 5%
Veterinary Science and Veterinary Medicine 1 5%
Immunology and Microbiology 1 5%
Other 1 5%
Unknown 10 48%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 March 2014.
All research outputs
#20,223,099
of 22,747,498 outputs
Outputs from Journal of Translational Medicine
#3,305
of 3,976 outputs
Outputs of similar age
#189,889
of 221,372 outputs
Outputs of similar age from Journal of Translational Medicine
#37
of 59 outputs
Altmetric has tracked 22,747,498 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,976 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 221,372 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 59 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.