Title |
TGFβR2 is a major target of miR-93 in nasopharyngeal carcinoma aggressiveness
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Published in |
Molecular Cancer, March 2014
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DOI | 10.1186/1476-4598-13-51 |
Pubmed ID | |
Authors |
Xiaoming Lyu, Weiyi Fang, Longmei Cai, Hang Zheng, Yanfen Ye, Lan Zhang, Jinbang li, Hong Peng, William C S Cho, Ena Wang, Francesco M Marincola, Kaitai Yao, Hongbing Cai, Jiliang Li, Xin Li |
Abstract |
MiR-17-92 cluster and its paralogues have emerged as crucial regulators of many oncogenes and tumor suppressors. Transforming growth factor-β receptor II (TGFβR2), as an important tumor suppressor, is involved in various cancer types. However, it is in cancer that only two miRNAs of this cluster and its paralogues have been reported so far to regulate TGFβR2. MiR-93 is oncogenic, but its targetome in cancer has not been fully defined. The role of miR-93 in nasopharyngeal carcinoma (NPC) still remains largely unknown. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 5 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 2 | 40% |
Scientists | 2 | 40% |
Members of the public | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 3% |
Unknown | 36 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 9 | 24% |
Student > Bachelor | 5 | 14% |
Researcher | 5 | 14% |
Student > Master | 5 | 14% |
Student > Doctoral Student | 2 | 5% |
Other | 6 | 16% |
Unknown | 5 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 18 | 49% |
Biochemistry, Genetics and Molecular Biology | 8 | 22% |
Agricultural and Biological Sciences | 4 | 11% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Social Sciences | 1 | 3% |
Other | 1 | 3% |
Unknown | 4 | 11% |