Title |
There is a specific response to pH by isolates of Haemophilus influenzae and this has a direct influence on biofilm formation
|
---|---|
Published in |
BMC Microbiology, February 2014
|
DOI | 10.1186/1471-2180-14-47 |
Pubmed ID | |
Authors |
Nadiah Ishak, Alexandra Tikhomirova, Stephen J Bent, Garth D Ehrlich, Fen Z Hu, Stephen P Kidd |
Abstract |
Haemophilus influenzae colonizes the nasopharynx as a commensal. Strain-specific factors allow some strains to migrate to particular anatomical niches, such as the middle ear, bronchi or blood, and induce disease by surviving within the conditions present at these sites in the body. It is established that H. influenzae colonization and in some cases survival is highly dependent on their ability to form a biofilm. Biofilm formation is a key trait in the development of chronic infection by certain isolates. This is exemplified by the contrast between the biofilm-forming strains found in middle ear infections and those isolates that survive within the blood and are rarely associated with biofilm development. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 1 | 20% |
United States | 1 | 20% |
Spain | 1 | 20% |
Unknown | 2 | 40% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 60% |
Scientists | 2 | 40% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 3% |
Germany | 1 | 3% |
Unknown | 35 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 8 | 22% |
Student > Ph. D. Student | 7 | 19% |
Student > Master | 4 | 11% |
Student > Postgraduate | 3 | 8% |
Student > Doctoral Student | 2 | 5% |
Other | 6 | 16% |
Unknown | 7 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 16 | 43% |
Medicine and Dentistry | 7 | 19% |
Immunology and Microbiology | 4 | 11% |
Biochemistry, Genetics and Molecular Biology | 2 | 5% |
Engineering | 1 | 3% |
Other | 0 | 0% |
Unknown | 7 | 19% |