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Aggregated n-of-1 trials of central nervous system stimulants versus placebo for paediatric traumatic brain injury – a pilot study

Overview of attention for article published in Trials, February 2014
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Title
Aggregated n-of-1 trials of central nervous system stimulants versus placebo for paediatric traumatic brain injury – a pilot study
Published in
Trials, February 2014
DOI 10.1186/1745-6215-15-54
Pubmed ID
Authors

Catherine J Nikles, Lynne McKinlay, Geoffrey K Mitchell, Sue-Ann S Carmont, Hugh E Senior, Mary-Clare A Waugh, Adrienne Epps, Philip J Schluter, Owen T Lloyd

Abstract

In 2006 there were 432,700 people in Australia who had acquired brain injury (ABI) with some limitation of activities; 90% of these were traumatic brain injuries (TBIs) and nearly a third sustained injury below age 15 years. One to four years post injury, 20% to 46% of children with traumatic brain injury (TBI) have clinically significant disorders of attention. There is controversy as to whether central nervous system (CNS) stimulants can be an effective method of treating these.Objectives were to determine the efficacy of CNS stimulants for children with TBI, and to calculate the sample size for a larger trial using the Conners' 3 Parent Rating Scales Score as the primary endpoint.

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Mendeley readers

The data shown below were compiled from readership statistics for 150 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 <1%
Unknown 149 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 23 15%
Student > Master 18 12%
Student > Ph. D. Student 15 10%
Student > Bachelor 14 9%
Other 11 7%
Other 26 17%
Unknown 43 29%
Readers by discipline Count As %
Psychology 28 19%
Medicine and Dentistry 27 18%
Neuroscience 11 7%
Agricultural and Biological Sciences 8 5%
Nursing and Health Professions 7 5%
Other 18 12%
Unknown 51 34%