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Paroxetine ameliorates lipopolysaccharide-induced microglia activation via differential regulation of MAPK signaling

Overview of attention for article published in Journal of Neuroinflammation, March 2014
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  • Average Attention Score compared to outputs of the same age
  • Above-average Attention Score compared to outputs of the same age and source (64th percentile)

Mentioned by

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3 X users
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1 Google+ user

Citations

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69 Dimensions

Readers on

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94 Mendeley
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1 CiteULike
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Title
Paroxetine ameliorates lipopolysaccharide-induced microglia activation via differential regulation of MAPK signaling
Published in
Journal of Neuroinflammation, March 2014
DOI 10.1186/1742-2094-11-47
Pubmed ID
Authors

Rong-Pei Liu, Ming Zou, Jian-Yong Wang, Juan-Juan Zhu, Jun-Mei Lai, Li-Li Zhou, Song-Fang Chen, Xiong Zhang, Jian-Hong Zhu

Abstract

Paroxetine, a selective serotonin reuptake inhibitor for counteracting depression, has been recently suggested as having a role in prevention of dopaminergic neuronal degeneration in substantia nigra, a hallmark of Parkinson's disease (PD). The pathogenesis of this type of neurological disorders often involves the activation of microglia and associated inflammatory processes. Thus in this study we aimed to understand the role of paroxetine in microglia activation and to elucidate the underlying mechanism(s).

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 94 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 1%
United States 1 1%
Unknown 92 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 22 23%
Student > Master 18 19%
Student > Bachelor 13 14%
Researcher 13 14%
Other 5 5%
Other 5 5%
Unknown 18 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 20%
Medicine and Dentistry 15 16%
Neuroscience 10 11%
Psychology 8 9%
Biochemistry, Genetics and Molecular Biology 7 7%
Other 13 14%
Unknown 22 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 September 2014.
All research outputs
#13,404,726
of 22,747,498 outputs
Outputs from Journal of Neuroinflammation
#1,440
of 2,617 outputs
Outputs of similar age
#109,533
of 221,230 outputs
Outputs of similar age from Journal of Neuroinflammation
#12
of 39 outputs
Altmetric has tracked 22,747,498 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,617 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 221,230 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.