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Aphrodisiac potentials of the ethanol extract of Aloe barbadensis Mill. root in male Wistar rats

Overview of attention for article published in BMC Complementary and Alternative Medicine, July 2017
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Title
Aphrodisiac potentials of the ethanol extract of Aloe barbadensis Mill. root in male Wistar rats
Published in
BMC Complementary and Alternative Medicine, July 2017
DOI 10.1186/s12906-017-1866-1
Pubmed ID
Authors

Joseph O. Erhabor, MacDonald Idu

Abstract

Aloe barbadensis (AB) is a short stemmed succulent medicinal herb that is being used by locals in Nigeria to enhance libido. Therefore this study evaluates the aphrodisiac potential and acute toxicological effect of A. barbadensis (AB) root in male Wistar rats. Aphrodisiac potential was determined following the oral administration of graded doses (100, 200 and 400 mg/kg) of ethanol extract of A. barbadensis root. Sildenafil citrate (Viagra) and distilled water served as positive and negative controls respectively. Sexual behavioural parameters (mounting and intromission frequencies, mounting, intromission and ejaculatory latencies) were observed. Serum testosterone and cholesterol concentrations were also progressively monitored on days 1, 7 and 14. The acute toxicological evaluation of the plant were based on any onset behavioural changes and mortality respectively. The findings from the sexual behavioural study indicated that the ethanol extract of A. barbadensis significantly increased mounting frequency and intromission frequency but significantly decreased mount and intromission latencies in a dose dependent manner particularly on day 1 and 14. The ethanol extract also prolonged ejaculatory latency. The testosterone and cholesterol concentrations were also increased as the dose increased particularly on day 1 and 7. The lowest dose of 100 mg/kg showed the best aphrodisiac effect. The toxicity studies showed that there were no acute behavioural changes with zero mortality. The increased blood testosterone and cholesterol concentrations by the ethanol extract of A. barbadensis can probably be said to be the possible mechanisms of action for its aphrodisiac property. The plant may also be used to treat hypotestosteronemia following its ability to increase testosterone. These findings therefore give backing to the acclaimed local use of A. barbadensis root as an aphrodisiac in males.

Twitter Demographics

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Mendeley readers

The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 69 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 13%
Student > Master 7 10%
Student > Bachelor 6 9%
Lecturer 5 7%
Student > Postgraduate 5 7%
Other 7 10%
Unknown 30 43%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 10 14%
Agricultural and Biological Sciences 6 9%
Medicine and Dentistry 5 7%
Biochemistry, Genetics and Molecular Biology 4 6%
Nursing and Health Professions 2 3%
Other 9 13%
Unknown 33 48%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 October 2021.
All research outputs
#16,195,506
of 20,858,036 outputs
Outputs from BMC Complementary and Alternative Medicine
#1,910
of 3,011 outputs
Outputs of similar age
#197,538
of 281,470 outputs
Outputs of similar age from BMC Complementary and Alternative Medicine
#3
of 3 outputs
Altmetric has tracked 20,858,036 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,011 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 281,470 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.