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What is the future of targeted therapy in rheumatology: biologics or small molecules?

Overview of attention for article published in BMC Medicine, March 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (76th percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

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5 X users
patent
1 patent
facebook
1 Facebook page

Citations

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92 Dimensions

Readers on

mendeley
187 Mendeley
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Title
What is the future of targeted therapy in rheumatology: biologics or small molecules?
Published in
BMC Medicine, March 2014
DOI 10.1186/1741-7015-12-43
Pubmed ID
Authors

Attila Mócsai, László Kovács, Péter Gergely

Abstract

Until late in the 20th century, the therapy of rheumatic diseases relied on the use of drugs that had been developed through empirical approaches without detailed understanding of the molecular mechanisms involved. That approach changed with the introduction of biologic therapeutics at the end of the 20th century and by the recent development of small-molecule inhibitors of intracellular signal transduction pathways. Here we compare and discuss the advantages and disadvantages of those two groups of targeted anti-inflammatory therapeutics.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 187 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 1%
Germany 1 <1%
Netherlands 1 <1%
Argentina 1 <1%
Canada 1 <1%
Japan 1 <1%
Denmark 1 <1%
Unknown 179 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 34 18%
Researcher 28 15%
Student > Ph. D. Student 21 11%
Student > Bachelor 21 11%
Other 18 10%
Other 36 19%
Unknown 29 16%
Readers by discipline Count As %
Medicine and Dentistry 52 28%
Agricultural and Biological Sciences 22 12%
Pharmacology, Toxicology and Pharmaceutical Science 18 10%
Biochemistry, Genetics and Molecular Biology 16 9%
Chemistry 14 7%
Other 27 14%
Unknown 38 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 October 2019.
All research outputs
#5,489,247
of 22,747,498 outputs
Outputs from BMC Medicine
#2,204
of 3,413 outputs
Outputs of similar age
#51,173
of 221,235 outputs
Outputs of similar age from BMC Medicine
#39
of 56 outputs
Altmetric has tracked 22,747,498 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,413 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.5. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 221,235 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.