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SMAD4 Loss triggers the phenotypic changes of pancreatic ductal adenocarcinoma cells

Overview of attention for article published in BMC Cancer, March 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

Mentioned by

blogs
1 blog
twitter
2 X users

Citations

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53 Dimensions

Readers on

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64 Mendeley
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Title
SMAD4 Loss triggers the phenotypic changes of pancreatic ductal adenocarcinoma cells
Published in
BMC Cancer, March 2014
DOI 10.1186/1471-2407-14-181
Pubmed ID
Authors

Yu-Wen Chen, Pi-Jung Hsiao, Ching-Chieh Weng, Kung-Kai Kuo, Tzu-Lei Kuo, Deng-Chyang Wu, Wen-Chun Hung, Kuang-Hung Cheng

Abstract

SMAD4 is a gastrointestinal malignancy-specific tumor suppressor gene found mutated in one third of colorectal cancer specimens and half of pancreatic tumors. SMAD4 inactivation by allelic deletion or intragenic mutation mainly occurs in the late stage of human pancreatic ductal adenocarcinoma (PDAC). Various studies have proposed potential SMAD4-mediated anti-tumor effects in human malignancy; however, the relevance of SMAD4 in the PDAC molecular phenotype has not yet been fully characterized.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 2%
Unknown 63 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 12 19%
Student > Ph. D. Student 11 17%
Researcher 7 11%
Other 5 8%
Student > Master 5 8%
Other 10 16%
Unknown 14 22%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 20 31%
Agricultural and Biological Sciences 13 20%
Medicine and Dentistry 11 17%
Immunology and Microbiology 2 3%
Psychology 1 2%
Other 3 5%
Unknown 14 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 June 2016.
All research outputs
#3,775,334
of 22,747,498 outputs
Outputs from BMC Cancer
#891
of 8,273 outputs
Outputs of similar age
#37,742
of 220,990 outputs
Outputs of similar age from BMC Cancer
#19
of 137 outputs
Altmetric has tracked 22,747,498 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,273 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 220,990 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 137 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.