You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
Attention Score in Context
| Title |
Growth differentiation factor 6 and transforming growth factor-beta differentially mediate mesenchymal stem cell differentiation, composition, and micromechanical properties of nucleus pulposus constructs
|
|---|---|
| Published in |
Arthritis Research & Therapy, March 2014
|
| DOI | 10.1186/ar4505 |
| Pubmed ID | |
| Authors |
Louise E Clarke, James C McConnell, Michael J Sherratt, Brian Derby, Stephen M Richardson, Judith A Hoyland |
| Abstract |
Currently, there is huge research focus on the development of novel cell based regeneration and tissue engineering therapies for the treatment of intervertebral disc degeneration and the associated back pain. Both bone marrow-derived (BM) mesenchymal stem cells (MSCs) and adipose-derived MSCs (AD-MSCs) are proposed as suitable cells for such therapies. However, currently there is no consensus as to the optimum growth factor needed to drive differentiation to a nucleus pulposus (NP)-like phenotype. The aim of this study was to investigate the effect of growth differentiation factor-6 (GDF6), compared to other transforming growth factor (TGF) superfamily members, on discogenic differentiation of MSCs, the matrix composition and micromechanics of engineered NP tissue constructs. |
Mendeley readers
The data shown below were compiled from readership statistics for 129 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 3% |
| United Kingdom | 3 | 2% |
| Unknown | 122 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 27 | 21% |
| Unspecified | 15 | 12% |
| Student > Master | 15 | 12% |
| Student > Bachelor | 15 | 12% |
| Researcher | 12 | 9% |
| Other | 20 | 16% |
| Unknown | 25 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 20 | 16% |
| Medicine and Dentistry | 19 | 15% |
| Agricultural and Biological Sciences | 16 | 12% |
| Unspecified | 15 | 12% |
| Engineering | 12 | 9% |
| Other | 17 | 13% |
| Unknown | 30 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 March 2014.
All research outputs
#17,285,668
of 25,373,627 outputs
Outputs from Arthritis Research & Therapy
#2,536
of 3,381 outputs
Outputs of similar age
#142,444
of 235,695 outputs
Outputs of similar age from Arthritis Research & Therapy
#28
of 58 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,381 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 235,695 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.