Title |
The MedSeq Project: a randomized trial of integrating whole genome sequencing into clinical medicine
|
---|---|
Published in |
Trials, March 2014
|
DOI | 10.1186/1745-6215-15-85 |
Pubmed ID | |
Authors |
Jason L Vassy, Denise M Lautenbach, Heather M McLaughlin, Sek Won Kong, Kurt D Christensen, Joel Krier, Isaac S Kohane, Lindsay Z Feuerman, Jennifer Blumenthal-Barby, J Scott Roberts, Lisa Soleymani Lehmann, Carolyn Y Ho, Peter A Ubel, Calum A MacRae, Christine E Seidman, Michael F Murray, Amy L McGuire, Heidi L Rehm, Robert C Green, for the MedSeq Project |
Abstract |
Whole genome sequencing (WGS) is already being used in certain clinical and research settings, but its impact on patient well-being, health-care utilization, and clinical decision-making remains largely unstudied. It is also unknown how best to communicate sequencing results to physicians and patients to improve health. We describe the design of the MedSeq Project: the first randomized trials of WGS in clinical care. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 23 | 49% |
United Kingdom | 3 | 6% |
France | 2 | 4% |
Austria | 1 | 2% |
Russia | 1 | 2% |
Nigeria | 1 | 2% |
Canada | 1 | 2% |
Australia | 1 | 2% |
Netherlands | 1 | 2% |
Other | 0 | 0% |
Unknown | 13 | 28% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 23 | 49% |
Scientists | 19 | 40% |
Practitioners (doctors, other healthcare professionals) | 4 | 9% |
Science communicators (journalists, bloggers, editors) | 1 | 2% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 5 | 2% |
Germany | 2 | <1% |
Switzerland | 1 | <1% |
United Kingdom | 1 | <1% |
France | 1 | <1% |
Rwanda | 1 | <1% |
Belgium | 1 | <1% |
Unknown | 266 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 52 | 19% |
Student > Master | 49 | 18% |
Student > Ph. D. Student | 34 | 12% |
Other | 28 | 10% |
Student > Bachelor | 21 | 8% |
Other | 50 | 18% |
Unknown | 44 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 51 | 18% |
Medicine and Dentistry | 51 | 18% |
Agricultural and Biological Sciences | 32 | 12% |
Psychology | 16 | 6% |
Social Sciences | 14 | 5% |
Other | 51 | 18% |
Unknown | 63 | 23% |