Title |
Forced arm use is superior to voluntary training for motor recovery and brain plasticity after cortical ischemia in rats
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Published in |
Experimental & Translational Stroke Medicine, February 2014
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DOI | 10.1186/2040-7378-6-3 |
Pubmed ID | |
Authors |
Armin Schneider, Andreas Rogalewski, Oliver Wafzig, Friederike Kirsch, Norbert Gretz, Carola Krüger, Kai Diederich, Claudia Pitzer, Rico Laage, Christian Plaas, Gerhard Vogt, Jens Minnerup, Wolf-Rüdiger Schäbitz |
Abstract |
Both the immobilization of the unaffected arm combined with physical therapy (forced arm use, FAU) and voluntary exercise (VE) as model for enriched environment are promising approaches to enhance recovery after stroke. The genomic mechanisms involved in long-term plasticity changes after different means of rehabilitative training post-stroke are largely unexplored. The present investigation explored the effects of these physical therapies on behavioral recovery and molecular markers of regeneration after experimental ischemia. |
X Demographics
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United States | 1 | 100% |
Demographic breakdown
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 1% |
Unknown | 72 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 14 | 19% |
Student > Bachelor | 10 | 14% |
Student > Ph. D. Student | 9 | 12% |
Student > Master | 9 | 12% |
Student > Doctoral Student | 7 | 10% |
Other | 14 | 19% |
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Biochemistry, Genetics and Molecular Biology | 3 | 4% |
Other | 9 | 12% |
Unknown | 13 | 18% |