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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Effects of cytosine methylation on transcription factor binding sites
|
|---|---|
| Published in |
BMC Genomics, March 2014
|
| DOI | 10.1186/1471-2164-15-119 |
| Pubmed ID | |
| Authors |
Yulia A Medvedeva, Abdullah M Khamis, Ivan V Kulakovskiy, Wail Ba-Alawi, Md Shariful I Bhuyan, Hideya Kawaji, Timo Lassmann, Matthias Harbers, Alistair RR Forrest, Vladimir B Bajic, The FANTOM consortium |
| Abstract |
DNA methylation in promoters is closely linked to downstream gene repression. However, whether DNA methylation is a cause or a consequence of gene repression remains an open question. If it is a cause, then DNA methylation may affect the affinity of transcription factors (TFs) for their binding sites (TFBSs). If it is a consequence, then gene repression caused by chromatin modification may be stabilized by DNA methylation. Until now, these two possibilities have been supported only by non-systematic evidence and they have not been tested on a wide range of TFs. An average promoter methylation is usually used in studies, whereas recent results suggested that methylation of individual cytosines can also be important. |
X Demographics
The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 25% |
| United Kingdom | 1 | 13% |
| Japan | 1 | 13% |
| Belgium | 1 | 13% |
| Unknown | 3 | 38% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 5 | 63% |
| Members of the public | 3 | 38% |
Mendeley readers
The data shown below were compiled from readership statistics for 331 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | <1% |
| United Kingdom | 2 | <1% |
| Netherlands | 2 | <1% |
| India | 1 | <1% |
| Norway | 1 | <1% |
| Belgium | 1 | <1% |
| Canada | 1 | <1% |
| Japan | 1 | <1% |
| Spain | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 318 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 93 | 28% |
| Researcher | 58 | 18% |
| Student > Master | 47 | 14% |
| Student > Bachelor | 38 | 11% |
| Student > Doctoral Student | 22 | 7% |
| Other | 42 | 13% |
| Unknown | 31 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 138 | 42% |
| Biochemistry, Genetics and Molecular Biology | 91 | 27% |
| Medicine and Dentistry | 14 | 4% |
| Computer Science | 9 | 3% |
| Chemistry | 5 | 2% |
| Other | 29 | 9% |
| Unknown | 45 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 July 2018.
All research outputs
#6,270,275
of 22,749,166 outputs
Outputs from BMC Genomics
#2,730
of 10,636 outputs
Outputs of similar age
#59,955
of 224,560 outputs
Outputs of similar age from BMC Genomics
#25
of 158 outputs
Altmetric has tracked 22,749,166 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 10,636 research outputs from this source. They receive a mean Attention Score of 4.7. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 224,560 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 158 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.