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Lack of timely accrual information in oncology clinical trials: a cross-sectional analysis

Overview of attention for article published in Trials, March 2014
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Title
Lack of timely accrual information in oncology clinical trials: a cross-sectional analysis
Published in
Trials, March 2014
DOI 10.1186/1745-6215-15-92
Pubmed ID
Authors

Aaron P Mitchell, Bradford R Hirsch, Amy P Abernethy

Abstract

Poor accrual is a significant barrier to the successful completion of oncology clinical trials; half of all phase 3 oncology trials close due to insufficient accrual. Timely access to accrual data fosters an understanding of successful trial design and can be used to inform the design of new clinical trials prospectively. Accrual statistics are available within research networks, such as the cancer cooperative groups, but comprehensive data reflecting the overall portfolio of cancer clinical trials are lacking. As a demonstration case, the purpose of this study was to quantify the public availability of accrual data across all recent renal cell carcinoma (RCC) trials.

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Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 33%
Researcher 4 15%
Student > Master 4 15%
Professor 2 7%
Student > Bachelor 2 7%
Other 1 4%
Unknown 5 19%
Readers by discipline Count As %
Medicine and Dentistry 10 37%
Nursing and Health Professions 3 11%
Psychology 2 7%
Business, Management and Accounting 1 4%
Computer Science 1 4%
Other 3 11%
Unknown 7 26%