Title |
Lack of timely accrual information in oncology clinical trials: a cross-sectional analysis
|
---|---|
Published in |
Trials, March 2014
|
DOI | 10.1186/1745-6215-15-92 |
Pubmed ID | |
Authors |
Aaron P Mitchell, Bradford R Hirsch, Amy P Abernethy |
Abstract |
Poor accrual is a significant barrier to the successful completion of oncology clinical trials; half of all phase 3 oncology trials close due to insufficient accrual. Timely access to accrual data fosters an understanding of successful trial design and can be used to inform the design of new clinical trials prospectively. Accrual statistics are available within research networks, such as the cancer cooperative groups, but comprehensive data reflecting the overall portfolio of cancer clinical trials are lacking. As a demonstration case, the purpose of this study was to quantify the public availability of accrual data across all recent renal cell carcinoma (RCC) trials. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 6 | 67% |
United States | 1 | 11% |
Unknown | 2 | 22% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 44% |
Practitioners (doctors, other healthcare professionals) | 3 | 33% |
Scientists | 2 | 22% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 27 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 9 | 33% |
Researcher | 4 | 15% |
Student > Master | 4 | 15% |
Professor | 2 | 7% |
Student > Bachelor | 2 | 7% |
Other | 1 | 4% |
Unknown | 5 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 10 | 37% |
Nursing and Health Professions | 3 | 11% |
Psychology | 2 | 7% |
Business, Management and Accounting | 1 | 4% |
Computer Science | 1 | 4% |
Other | 3 | 11% |
Unknown | 7 | 26% |