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Nuclear protein in testis carcinoma of the mediastinum: a case report

Overview of attention for article published in Journal of Medical Case Reports, June 2017
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Title
Nuclear protein in testis carcinoma of the mediastinum: a case report
Published in
Journal of Medical Case Reports, June 2017
DOI 10.1186/s13256-017-1328-x
Pubmed ID
Authors

Gonçalo Boleto, Jeanne-Marie Perotin, Claire Launois, Emmanuelle Uro-Coste, Philippe Birembaut, Sandra Dury, Hervé Vallerand, François Lebargy, Gaëtan Deslée, Juliette Vella-Boucaud

Abstract

Nuclear protein in testis carcinoma is a rare and very aggressive undifferentiated cancer which characteristically arises in the midline of the head, neck, and mediastinum. We describe the case of a 46-year-old white woman admitted for superior vena cava syndrome revealing a mediastinal tumor. Pathological examination of specimens obtained by mediastinoscopy revealed an undifferentiated tumor with solid growth and positive immunoreactivity for p40 and negative immunoreactivity for cytokeratin markers. Immunohistochemical staining was positive for nuclear protein in testis, allowing the diagnosis of nuclear protein in testis midline carcinoma of the mediastinum. We present a rare case of mediastinal nuclear protein in testis carcinoma with diagnosis based on nuclear protein in testis protein positivity and atypical immunohistochemical features including p40 positivity and anti-cytokeratin negativity. Physicians must remain aware of the possibility of nuclear protein in testis carcinoma especially in young patients with thoracic symptoms and suspicion of neoplasm.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 7 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 7 100%

Demographic breakdown

Readers by professional status Count As %
Other 1 14%
Professor 1 14%
Student > Ph. D. Student 1 14%
Researcher 1 14%
Student > Postgraduate 1 14%
Other 0 0%
Unknown 2 29%
Readers by discipline Count As %
Medicine and Dentistry 2 29%
Psychology 1 14%
Nursing and Health Professions 1 14%
Unknown 3 43%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 July 2017.
All research outputs
#20,436,330
of 22,990,068 outputs
Outputs from Journal of Medical Case Reports
#3,507
of 3,942 outputs
Outputs of similar age
#275,794
of 317,116 outputs
Outputs of similar age from Journal of Medical Case Reports
#59
of 77 outputs
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