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Curcumin: the spicy modulator of breast carcinogenesis

Overview of attention for article published in Journal of Experimental & Clinical Cancer Research, July 2017
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (64th percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

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6 X users
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2 YouTube creators

Citations

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114 Dimensions

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208 Mendeley
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Title
Curcumin: the spicy modulator of breast carcinogenesis
Published in
Journal of Experimental & Clinical Cancer Research, July 2017
DOI 10.1186/s13046-017-0566-5
Pubmed ID
Authors

Urmila Banik, Subramani Parasuraman, Arun Kumar Adhikary, Nor Hayati Othman

Abstract

Worldwide breast cancer is the most common cancer in women. For many years clinicians and the researchers are examining and exploring various therapeutic modalities for breast cancer. Yet the disease has remained unconquered and the quest for cure is still going on. Present-day strategy of breast cancer therapy and prevention is either combination of a number of drugs or a drug that modulates multiple targets. In this regard natural products are now becoming significant options. Curcumin exemplifies a promising natural anticancer agent for this purpose. This review primarily underscores the modulatory effect of curcumin on the cancer hallmarks. The focus is its anticancer effect in the complex pathways of breast carcinogenesis. Curcumin modulates breast carcinogenesis through its effect on cell cycle and proliferation, apoptosis, senescence, cancer spread and angiogenesis. Largely the NFkB, PI3K/Akt/mTOR, MAPK and JAK/STAT are the key signaling pathways involved. The review also highlights the curcumin mediated modulation of tumor microenvironment, cancer immunity, breast cancer stem cells and cancer related miRNAs. Using curcumin as a therapeutic and preventive agent in breast cancer is perplexed by its diverse biological activity, much of which remains inexplicable. The information reviewed here should point toward potential scope of future curcumin research in breast cancer.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 208 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 208 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 40 19%
Student > Bachelor 27 13%
Student > Ph. D. Student 24 12%
Student > Doctoral Student 15 7%
Researcher 8 4%
Other 32 15%
Unknown 62 30%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 35 17%
Medicine and Dentistry 32 15%
Pharmacology, Toxicology and Pharmaceutical Science 20 10%
Agricultural and Biological Sciences 12 6%
Nursing and Health Professions 8 4%
Other 29 14%
Unknown 72 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 February 2023.
All research outputs
#7,780,614
of 25,382,440 outputs
Outputs from Journal of Experimental & Clinical Cancer Research
#478
of 2,380 outputs
Outputs of similar age
#113,367
of 325,062 outputs
Outputs of similar age from Journal of Experimental & Clinical Cancer Research
#4
of 25 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 2,380 research outputs from this source. They receive a mean Attention Score of 4.8. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 325,062 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.