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Is polymyxin B-immobilized fiber column ineffective for septic shock? A discussion on the press release for EUPHRATES trial

Overview of attention for article published in Journal of Intensive Care, July 2017
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1 tweeter

Citations

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25 Dimensions

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23 Mendeley
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Title
Is polymyxin B-immobilized fiber column ineffective for septic shock? A discussion on the press release for EUPHRATES trial
Published in
Journal of Intensive Care, July 2017
DOI 10.1186/s40560-017-0236-x
Pubmed ID
Authors

Toshiaki Iba, Lucy Fowler

Abstract

The efficacy of polymyxin B-immobilized (PMX) fiber column on septic shock is still under debate. Recently, the result from "Evaluating the Use of Polymyxin B Hemoperfusion in a Randomized controlled trial of Adults Treated for Endotoxemia and Septic shock (EUPHRATES)" trial has been announced as a press release. According to that report, less than a 5% mortality difference was recognized in the "per protocol population" (n = 244, 31.9 vs. 36.9%) and the decrease was not statistically significant. However, among the patients in refractory shock with a multiple organ dysfunction score of more than 9 and an EAA between 0.6 and 0.9, a 10.7% reduction in 28-day mortality was recognized (p = 0.0474) when they received two sessions of hemoperfusion using the PMX fiber column. Since this favorable effect was obtained from "post hoc" analysis, further study is expected.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 23 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 22%
Other 4 17%
Professor > Associate Professor 3 13%
Student > Postgraduate 2 9%
Student > Master 2 9%
Other 3 13%
Unknown 4 17%
Readers by discipline Count As %
Medicine and Dentistry 15 65%
Chemical Engineering 1 4%
Environmental Science 1 4%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Unknown 5 22%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 July 2017.
All research outputs
#7,163,649
of 11,498,428 outputs
Outputs from Journal of Intensive Care
#175
of 235 outputs
Outputs of similar age
#150,415
of 261,722 outputs
Outputs of similar age from Journal of Intensive Care
#16
of 23 outputs
Altmetric has tracked 11,498,428 research outputs across all sources so far. This one is in the 23rd percentile – i.e., 23% of other outputs scored the same or lower than it.
So far Altmetric has tracked 235 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 261,722 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.