Title |
Marek’s disease virus and skin interactions
|
---|---|
Published in |
Veterinary Research, April 2014
|
DOI | 10.1186/1297-9716-45-36 |
Pubmed ID | |
Authors |
Mathilde Couteaudier, Caroline Denesvre |
Abstract |
Marek's disease virus (MDV) is a highly contagious herpesvirus which induces T-cell lymphoma in the chicken. This virus is still spreading in flocks despite forty years of vaccination, with important economical losses worldwide. The feather follicles, which anchor feathers into the skin and allow their morphogenesis, are considered as the unique source of MDV excretion, causing environmental contamination and disease transmission. Epithelial cells from the feather follicles are the only known cells in which high levels of infectious mature virions have been observed by transmission electron microscopy and from which cell-free infectious virions have been purified. Finally, feathers harvested on animals and dust are today considered excellent materials to monitor vaccination, spread of pathogenic viruses, and environmental contamination. This article reviews the current knowledge on MDV-skin interactions and discusses new approaches that could solve important issues in the future. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Nigeria | 2 | 50% |
United Kingdom | 1 | 25% |
Unknown | 1 | 25% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Peru | 2 | 2% |
Germany | 1 | 1% |
Canada | 1 | 1% |
Unknown | 95 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 13 | 13% |
Student > Master | 13 | 13% |
Student > Bachelor | 13 | 13% |
Researcher | 11 | 11% |
Student > Doctoral Student | 9 | 9% |
Other | 17 | 17% |
Unknown | 23 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 24 | 24% |
Veterinary Science and Veterinary Medicine | 19 | 19% |
Biochemistry, Genetics and Molecular Biology | 13 | 13% |
Medicine and Dentistry | 5 | 5% |
Immunology and Microbiology | 4 | 4% |
Other | 9 | 9% |
Unknown | 25 | 25% |