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Leucine supplementation differentially enhances pancreatic cancer growth in lean and overweight mice

Overview of attention for article published in Cancer & Metabolism, March 2014
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (71st percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

twitter
5 tweeters
facebook
1 Facebook page
video
2 video uploaders

Citations

dimensions_citation
38 Dimensions

Readers on

mendeley
73 Mendeley
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Title
Leucine supplementation differentially enhances pancreatic cancer growth in lean and overweight mice
Published in
Cancer & Metabolism, March 2014
DOI 10.1186/2049-3002-2-6
Pubmed ID
Authors

Kristyn A Liu, Laura M Lashinger, Audrey J Rasmussen, Stephen D Hursting

Abstract

The risk of pancreatic cancer, the 4th deadliest cancer for both men and women in the United States, is increased by obesity. Calorie restriction (CR) is a well-known dietary regimen that prevents or reverses obesity and suppresses tumorigenesis in a variety of animal models, at least in part via inhibition of mammalian target of rapamycin (mTOR) signaling. Branched-chain amino acids (BCAA), especially leucine, activate mTOR and enhance growth and proliferation of myocytes and epithelial cells, which is why leucine is a popular supplement among athletes. Leucine is also increasingly being used as a treatment for pancreatic cancer cachexia, but the effects of leucine supplementation on pancreatic tumor growth have not been elucidated.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 73 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 22%
Researcher 10 14%
Student > Master 9 12%
Student > Bachelor 8 11%
Student > Doctoral Student 5 7%
Other 13 18%
Unknown 12 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 18 25%
Agricultural and Biological Sciences 12 16%
Medicine and Dentistry 11 15%
Pharmacology, Toxicology and Pharmaceutical Science 6 8%
Nursing and Health Professions 5 7%
Other 7 10%
Unknown 14 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 February 2016.
All research outputs
#5,186,841
of 17,362,547 outputs
Outputs from Cancer & Metabolism
#56
of 154 outputs
Outputs of similar age
#56,849
of 198,102 outputs
Outputs of similar age from Cancer & Metabolism
#1
of 5 outputs
Altmetric has tracked 17,362,547 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 154 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.9. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 198,102 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them