Title |
Acne and PCOS are less frequent in women with Mayer-Rokitansky-Küster-Hauser syndrome despite a high rate of hyperandrogenemia: a cross-sectional study
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Published in |
Reproductive Biology and Endocrinology, March 2014
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DOI | 10.1186/1477-7827-12-23 |
Pubmed ID | |
Authors |
Katharina Rall, Gabriele Conzelmann, Norbert Schäffeler, Melanie Henes, Diethelm Wallwiener, Matthias Möhrle, Sara Y Brucker |
Abstract |
Acne is a very common skin condition during adolescence and adulthood. Patients with uterovaginal agenesis (Mayer-Rokitansky-Küster-Hauser syndrome, MRKH) treated at the Tübingen University Center for Rare Female Genital Malformations, however, clinically appeared to be less frequently affected by acne. The etiology of MRKH syndrome remains unknown. The only known MRKH-associated mutations are located within the WNT4 gene and lead to an atypical form of MRKH syndrome associated with clinical and biochemical hyperandrogenism. Our study aimed to assess the frequency, severity, and self-evaluation of acne in MRKH patients and to correlate the clinical findings with hormone analyses. |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 30 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 5 | 17% |
Other | 3 | 10% |
Student > Doctoral Student | 3 | 10% |
Student > Master | 3 | 10% |
Lecturer | 1 | 3% |
Other | 5 | 17% |
Unknown | 10 | 33% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 5 | 17% |
Biochemistry, Genetics and Molecular Biology | 4 | 13% |
Agricultural and Biological Sciences | 4 | 13% |
Psychology | 2 | 7% |
Business, Management and Accounting | 1 | 3% |
Other | 2 | 7% |
Unknown | 12 | 40% |