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T-helper 17 cell cytokines and interferon type I: partners in crime in systemic lupus erythematosus?

Overview of attention for article published in Arthritis Research & Therapy, March 2014
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Title
T-helper 17 cell cytokines and interferon type I: partners in crime in systemic lupus erythematosus?
Published in
Arthritis Research & Therapy, March 2014
DOI 10.1186/ar4499
Pubmed ID
Authors

Zana Brkic, Odilia BJ Corneth, Cornelia G van Helden-Meeuwsen, Radboud JEM Dolhain, Naomi I Maria, Sandra MJ Paulissen, Nadine Davelaar, Jan Piet van Hamburg, Paul L van Daele, Virgil A Dalm, P Martin van Hagen, Johanna MW Hazes, Marjan A Versnel, Erik Lubberts

Abstract

A hallmark of systemic autoimmune diseases like systemic lupus erythematosus (SLE) is the increased expression of interferon (IFN) type I inducible genes, so-called IFN type I signature. Recently, T helper 17 subset (Th17 cells), which produces IL-17A, IL-17F, IL-21 and IL-22, has been implicated in SLE. As CCR6 enriches for Th17 cells, we used this approach to investigate whether CCR6+ memory T helper cells producing IL-17A, IL-17F, IL-21 and/or IL-22 are increased in SLE patients and whether this increase is related to the presence of IFN type I signature.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Spain 1 2%
United States 1 2%
Netherlands 1 2%
Unknown 37 90%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 22%
Researcher 6 15%
Student > Master 6 15%
Student > Doctoral Student 4 10%
Student > Bachelor 4 10%
Other 8 20%
Unknown 4 10%
Readers by discipline Count As %
Medicine and Dentistry 16 39%
Agricultural and Biological Sciences 8 20%
Immunology and Microbiology 6 15%
Biochemistry, Genetics and Molecular Biology 4 10%
Psychology 2 5%
Other 0 0%
Unknown 5 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 August 2015.
All research outputs
#20,657,128
of 25,374,917 outputs
Outputs from Arthritis Research & Therapy
#2,906
of 3,380 outputs
Outputs of similar age
#174,103
of 235,892 outputs
Outputs of similar age from Arthritis Research & Therapy
#43
of 58 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,380 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one is in the 7th percentile – i.e., 7% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 235,892 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.