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MEK targeting in N-RAS mutated metastatic melanoma

Overview of attention for article published in Molecular Cancer, March 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)

Mentioned by

twitter
1 tweeter
patent
2 patents

Citations

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51 Dimensions

Readers on

mendeley
51 Mendeley
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Title
MEK targeting in N-RAS mutated metastatic melanoma
Published in
Molecular Cancer, March 2014
DOI 10.1186/1476-4598-13-45
Pubmed ID
Authors

Jaykumar Thumar, David Shahbazian, Saadia A Aziz, Lucia B Jilaveanu, Harriet M Kluger

Abstract

Gain of function mutations in B-RAF and N-RAS occur frequently in melanoma, leading to mitogen activating protein kinase (MAPK) pathway activation, and this pathway is the target of drugs in development. Our purpose was to study clinical characteristics of patients with mutations in this pathway and to determine activity of inhibitors of B-RAF and MEK in short term cultures grown from tumors of some of these patients.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Ecuador 1 2%
Unknown 49 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 27%
Student > Master 9 18%
Student > Ph. D. Student 8 16%
Other 3 6%
Student > Postgraduate 3 6%
Other 7 14%
Unknown 7 14%
Readers by discipline Count As %
Medicine and Dentistry 12 24%
Agricultural and Biological Sciences 12 24%
Biochemistry, Genetics and Molecular Biology 10 20%
Immunology and Microbiology 2 4%
Neuroscience 2 4%
Other 4 8%
Unknown 9 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 August 2019.
All research outputs
#3,248,374
of 16,938,520 outputs
Outputs from Molecular Cancer
#135
of 1,342 outputs
Outputs of similar age
#38,599
of 197,209 outputs
Outputs of similar age from Molecular Cancer
#1
of 1 outputs
Altmetric has tracked 16,938,520 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,342 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 197,209 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them