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A novel molecular typing method of Mycobacteria based on DNA barcoding visualization

Overview of attention for article published in Journal of Clinical Bioinformatics, February 2014
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Title
A novel molecular typing method of Mycobacteria based on DNA barcoding visualization
Published in
Journal of Clinical Bioinformatics, February 2014
DOI 10.1186/2043-9113-4-4
Pubmed ID
Authors

Bin Liu, Xiaotian Zhang, Honglan Huang, Ying Zhang, Fengfeng Zhou, Guoqing Wang

Abstract

Different subtypes of Mycobacterium tuberculosis (MTB) may induce diverse severe human infections, and some of their symptoms are similar to other pathogenes, e.g. Nontuberculosis mycobacteria (NTM). So determination of mycobacterium subtypes facilitates the effective control of MTB infection and proliferation. This study exploits a novel DNA barcoding visualization method for molecular typing of 17 mycobacteria genomes published in the NCBI prokaryotic genome database. Three mycobacterium genes (Rv0279c, Rv3508 and Rv3514) from the PE/PPE family of MT Band were detected to best represent the inter-strain pathogenetic variations. An accurate and fast MTB substrain typing method was proposed based on the combination of the aforementioned three biomarker genes and the 16S rRNA gene. The protocol of establishing a bacterial substrain typing system used in this study may also be applied to the other pathogenes.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 1 5%
Unknown 18 95%

Demographic breakdown

Readers by professional status Count As %
Student > Master 6 32%
Researcher 5 26%
Lecturer > Senior Lecturer 2 11%
Student > Ph. D. Student 1 5%
Other 1 5%
Other 2 11%
Unknown 2 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 32%
Biochemistry, Genetics and Molecular Biology 5 26%
Medicine and Dentistry 3 16%
Immunology and Microbiology 2 11%
Computer Science 1 5%
Other 0 0%
Unknown 2 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 April 2014.
All research outputs
#20,656,820
of 25,374,647 outputs
Outputs from Journal of Clinical Bioinformatics
#44
of 61 outputs
Outputs of similar age
#177,006
of 238,973 outputs
Outputs of similar age from Journal of Clinical Bioinformatics
#3
of 4 outputs
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So far Altmetric has tracked 61 research outputs from this source. They receive a mean Attention Score of 3.1. This one is in the 3rd percentile – i.e., 3% of its peers scored the same or lower than it.
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