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The lamin protein family

Overview of attention for article published in Genome Biology, May 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (64th percentile)

Mentioned by

news
1 news outlet
wikipedia
2 Wikipedia pages

Citations

dimensions_citation
383 Dimensions

Readers on

mendeley
573 Mendeley
citeulike
2 CiteULike
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Title
The lamin protein family
Published in
Genome Biology, May 2011
DOI 10.1186/gb-2011-12-5-222
Pubmed ID
Authors

Travis A Dittmer, Tom Misteli

Abstract

The lamins are the major architectural proteins of the animal cell nucleus. Lamins line the inside of the nuclear membrane, where they provide a platform for the binding of proteins and chromatin and confer mechanical stability. They have been implicated in a wide range of nuclear functions, including higher-order genome organization, chromatin regulation, transcription, DNA replication and DNA repair. The lamins are members of the intermediate filament (IF) family of proteins, which constitute a major component of the cytoskeleton. Lamins are the only nuclear IFs and are the ancestral founders of the IF protein superfamily. Lamins polymerize into fibers forming a complex protein meshwork in vivo and, like all IF proteins, have a tripartite structure with two globular head and tail domains flanking a central α-helical rod domain, which supports the formation of higher-order polymers. Mutations in lamins cause a large number of diverse human diseases, collectively known as the laminopathies, underscoring their functional importance.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 573 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 <1%
Japan 3 <1%
United Kingdom 3 <1%
Brazil 1 <1%
Italy 1 <1%
Portugal 1 <1%
Russia 1 <1%
Switzerland 1 <1%
Canada 1 <1%
Other 1 <1%
Unknown 556 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 125 22%
Student > Master 85 15%
Student > Bachelor 81 14%
Researcher 74 13%
Student > Doctoral Student 31 5%
Other 63 11%
Unknown 114 20%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 186 32%
Agricultural and Biological Sciences 140 24%
Medicine and Dentistry 31 5%
Engineering 19 3%
Chemistry 13 2%
Other 51 9%
Unknown 133 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 March 2022.
All research outputs
#3,138,727
of 25,374,917 outputs
Outputs from Genome Biology
#2,318
of 4,467 outputs
Outputs of similar age
#14,767
of 122,210 outputs
Outputs of similar age from Genome Biology
#11
of 31 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one is in the 47th percentile – i.e., 47% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 122,210 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.