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Inflammatory modulation of exercise salience: using hormesis to return to a healthy lifestyle

Overview of attention for article published in Nutrition & Metabolism, January 2010
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)

Mentioned by

19 tweeters
2 Facebook pages


22 Dimensions

Readers on

98 Mendeley
2 CiteULike
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Inflammatory modulation of exercise salience: using hormesis to return to a healthy lifestyle
Published in
Nutrition & Metabolism, January 2010
DOI 10.1186/1743-7075-7-87
Pubmed ID

Alistair V Nunn, Geoffrey W Guy, James S Brodie, Jimmy D Bell


Most of the human population in the western world has access to unlimited calories and leads an increasingly sedentary lifestyle. The propensity to undertake voluntary exercise or indulge in spontaneous physical exercise, which might be termed "exercise salience", is drawing increased scientific attention. Despite its genetic aspects, this complex behaviour is clearly modulated by the environment and influenced by physiological states. Inflammation is often overlooked as one of these conditions even though it is known to induce a state of reduced mobility. Chronic subclinical inflammation is associated with the metabolic syndrome; a largely lifestyle-induced disease which can lead to decreased exercise salience. The result is a vicious cycle that increases oxidative stress and reduces metabolic flexibility and perpetuates the disease state. In contrast, hormetic stimuli can induce an anti-inflammatory phenotype, thereby enhancing exercise salience, leading to greater biological fitness and improved functional longevity. One general consequence of hormesis is upregulation of mitochondrial function and resistance to oxidative stress. Examples of hormetic factors include calorie restriction, extreme environmental temperatures, physical activity and polyphenols. The hormetic modulation of inflammation, and thus, exercise salience, may help to explain the highly heterogeneous expression of voluntary exercise behaviour and therefore body composition phenotypes of humans living in similar obesogenic environments.

Twitter Demographics

The data shown below were collected from the profiles of 19 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 98 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 1%
Netherlands 1 1%
Indonesia 1 1%
Pakistan 1 1%
New Zealand 1 1%
Belgium 1 1%
United States 1 1%
Unknown 91 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 13%
Student > Master 13 13%
Other 12 12%
Student > Bachelor 9 9%
Professor 8 8%
Other 34 35%
Unknown 9 9%
Readers by discipline Count As %
Medicine and Dentistry 19 19%
Agricultural and Biological Sciences 19 19%
Unspecified 8 8%
Biochemistry, Genetics and Molecular Biology 7 7%
Sports and Recreations 6 6%
Other 25 26%
Unknown 14 14%

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 April 2021.
All research outputs
of 21,028,682 outputs
Outputs from Nutrition & Metabolism
of 904 outputs
Outputs of similar age
of 207,060 outputs
Outputs of similar age from Nutrition & Metabolism
of 1 outputs
Altmetric has tracked 21,028,682 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 904 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 23.8. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 207,060 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them