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Angiogenesis is present in experimental autoimmune encephalomyelitis and pro-angiogenic factors are increased in multiple sclerosis lesions

Overview of attention for article published in Journal of Neuroinflammation, December 2010
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Title
Angiogenesis is present in experimental autoimmune encephalomyelitis and pro-angiogenic factors are increased in multiple sclerosis lesions
Published in
Journal of Neuroinflammation, December 2010
DOI 10.1186/1742-2094-7-95
Pubmed ID
Authors

Timothy J Seabrook, Amanda Littlewood-Evans, Volker Brinkmann, Bernadette Pöllinger, Christian Schnell, Peter C Hiestand

Abstract

Angiogenesis is a common finding in chronic inflammatory diseases; however, its role in multiple sclerosis (MS) is unclear. Central nervous system lesions from both MS and experimental autoimmune encephalomyelitis (EAE), the animal model of MS, contain T cells, macrophages and activated glia, which can produce pro-angiogenic factors. Previous EAE studies have demonstrated an increase in blood vessels, but differences between the different phases of disease have not been reported. Therefore we examined angiogenic promoting factors in MS and EAE lesions to determine if there were changes in blood vessel density at different stages of EAE.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 4%
United Kingdom 1 1%
India 1 1%
Canada 1 1%
Unknown 64 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 23%
Researcher 14 20%
Student > Doctoral Student 8 11%
Student > Bachelor 6 9%
Professor 4 6%
Other 14 20%
Unknown 8 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 24%
Neuroscience 15 21%
Medicine and Dentistry 13 19%
Biochemistry, Genetics and Molecular Biology 7 10%
Immunology and Microbiology 2 3%
Other 6 9%
Unknown 10 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 July 2011.
All research outputs
#20,712,517
of 23,312,088 outputs
Outputs from Journal of Neuroinflammation
#2,352
of 2,692 outputs
Outputs of similar age
#173,811
of 184,264 outputs
Outputs of similar age from Journal of Neuroinflammation
#32
of 33 outputs
Altmetric has tracked 23,312,088 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,692 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 184,264 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.