Title |
Strategies for aggregating gene expression data: The collapseRows R function
|
---|---|
Published in |
BMC Bioinformatics, August 2011
|
DOI | 10.1186/1471-2105-12-322 |
Pubmed ID | |
Authors |
Jeremy A Miller, Chaochao Cai, Peter Langfelder, Daniel H Geschwind, Sunil M Kurian, Daniel R Salomon, Steve Horvath |
Abstract |
Genomic and other high dimensional analyses often require one to summarize multiple related variables by a single representative. This task is also variously referred to as collapsing, combining, reducing, or aggregating variables. Examples include summarizing several probe measurements corresponding to a single gene, representing the expression profiles of a co-expression module by a single expression profile, and aggregating cell-type marker information to de-convolute expression data. Several standard statistical summary techniques can be used, but network methods also provide useful alternative methods to find representatives. Currently few collapsing functions are developed and widely applied. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 67% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 2 | 67% |
Members of the public | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 7 | 2% |
United Kingdom | 4 | 1% |
France | 2 | <1% |
Netherlands | 1 | <1% |
Portugal | 1 | <1% |
Sweden | 1 | <1% |
Israel | 1 | <1% |
India | 1 | <1% |
Germany | 1 | <1% |
Other | 4 | 1% |
Unknown | 295 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 95 | 30% |
Student > Ph. D. Student | 82 | 26% |
Student > Master | 22 | 7% |
Student > Bachelor | 18 | 6% |
Professor > Associate Professor | 14 | 4% |
Other | 55 | 17% |
Unknown | 32 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 101 | 32% |
Biochemistry, Genetics and Molecular Biology | 61 | 19% |
Computer Science | 25 | 8% |
Medicine and Dentistry | 23 | 7% |
Neuroscience | 20 | 6% |
Other | 44 | 14% |
Unknown | 44 | 14% |