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Cross-presentation of viral antigens in dribbles leads to efficient activation of virus-specific human memory t cells

Overview of attention for article published in Journal of Translational Medicine, April 2014
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Title
Cross-presentation of viral antigens in dribbles leads to efficient activation of virus-specific human memory t cells
Published in
Journal of Translational Medicine, April 2014
DOI 10.1186/1479-5876-12-100
Pubmed ID
Authors

Wei Ye, Yun Xing, Christopher Paustian, Rieneke van de Ven, Tarsem Moudgil, Traci L Hilton, Bernard A Fox, Walter J Urba, Wei Zhao, Hong-Ming Hu

Abstract

Autophagy regulates innate and adaptive immune responses to pathogens and tumors. We have reported that autophagosomes derived from tumor cells after proteasome inhibition, DRibbles (Defective ribosomal products in blebs), were excellent sources of antigens for efficient cross priming of tumor-specific CD8⁺ T cells, which mediated regression of established tumors in mice. But the activity of DRibbles in human has not been reported.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Venezuela, Bolivarian Republic of 1 2%
Canada 1 2%
Unknown 41 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 30%
Student > Ph. D. Student 9 21%
Student > Bachelor 5 12%
Other 4 9%
Student > Doctoral Student 3 7%
Other 5 12%
Unknown 4 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 35%
Immunology and Microbiology 7 16%
Medicine and Dentistry 5 12%
Biochemistry, Genetics and Molecular Biology 5 12%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 2 5%
Unknown 8 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 April 2014.
All research outputs
#20,228,193
of 22,753,345 outputs
Outputs from Journal of Translational Medicine
#3,305
of 3,977 outputs
Outputs of similar age
#173,170
of 203,744 outputs
Outputs of similar age from Journal of Translational Medicine
#37
of 69 outputs
Altmetric has tracked 22,753,345 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,977 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 203,744 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 69 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.