↓ Skip to main content

Hypoxia-inducible transcription factor-1α promotes hypoxia-induced A549 apoptosis via a mechanism that involves the glycolysis pathway

Overview of attention for article published in BMC Cancer, January 2006
Altmetric Badge

Mentioned by

f1000
1 research highlight platform

Citations

dimensions_citation
66 Dimensions

Readers on

mendeley
43 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Hypoxia-inducible transcription factor-1α promotes hypoxia-induced A549 apoptosis via a mechanism that involves the glycolysis pathway
Published in
BMC Cancer, January 2006
DOI 10.1186/1471-2407-6-26
Pubmed ID
Authors

FengMing Luo, XiaoJing Liu, NaiHong Yan, ShuangQing Li, GuiQun Cao, QingYing Cheng, QingJie Xia, HongJing Wang

Abstract

Hypoxia-inducible transcription factor-1alpha (HIF-1alpha), which plays an important role in controlling the hypoxia-induced glycolysis pathway, is a "master" gene in the tissue hypoxia response during tumor development. However, its role in the apoptosis of non-small cell lung cancer remains unknown. Here, we have studied the effects of HIF-1alpha on apoptosis by modulating HIF-1alpha gene expression in A549 cells through both siRNA knock-down and over-expression.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 43 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 35%
Student > Master 7 16%
Researcher 4 9%
Student > Bachelor 3 7%
Other 3 7%
Other 8 19%
Unknown 3 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 30%
Biochemistry, Genetics and Molecular Biology 10 23%
Medicine and Dentistry 8 19%
Unspecified 2 5%
Immunology and Microbiology 2 5%
Other 3 7%
Unknown 5 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 March 2006.
All research outputs
#15,233,109
of 22,649,029 outputs
Outputs from BMC Cancer
#4,097
of 8,235 outputs
Outputs of similar age
#131,496
of 154,259 outputs
Outputs of similar age from BMC Cancer
#11
of 15 outputs
Altmetric has tracked 22,649,029 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,235 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 154,259 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 4th percentile – i.e., 4% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.