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Oxidative and pro-inflammatory impact of regular and denicotinized cigarettes on blood brain barrier endothelial cells: is smoking reduced or nicotine-free products really safe?

Overview of attention for article published in BMC Neuroscience, April 2014
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • High Attention Score compared to outputs of the same age and source (82nd percentile)

Mentioned by

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2 X users
wikipedia
1 Wikipedia page

Citations

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101 Dimensions

Readers on

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88 Mendeley
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Title
Oxidative and pro-inflammatory impact of regular and denicotinized cigarettes on blood brain barrier endothelial cells: is smoking reduced or nicotine-free products really safe?
Published in
BMC Neuroscience, April 2014
DOI 10.1186/1471-2202-15-51
Pubmed ID
Authors

Pooja Naik, Neel Fofaria, Shikha Prasad, Ravi K Sajja, Babette Weksler, Pierre-Olivier Couraud, Ignacio A Romero, Luca Cucullo

Abstract

Both active and passive tobacco smoke (TS) potentially impair the vascular endothelial function in a causative and dose-dependent manner, largely related to the content of reactive oxygen species (ROS), nicotine, and pro-inflammatory activity. Together these factors can compromise the restrictive properties of the blood-brain barrier (BBB) and trigger the pathogenesis/progression of several neurological disorders including silent cerebral infarction, stroke, multiple sclerosis and Alzheimer's disease. Based on these premises, we analyzed and assessed the toxic impact of smoke extract from a range of tobacco products (with varying levels of nicotine) on brain microvascular endothelial cell line (hCMEC/D3), a well characterized human BBB model.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
United States 1 1%
Unknown 86 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 19 22%
Student > Bachelor 12 14%
Researcher 12 14%
Student > Doctoral Student 8 9%
Student > Master 7 8%
Other 16 18%
Unknown 14 16%
Readers by discipline Count As %
Medicine and Dentistry 23 26%
Biochemistry, Genetics and Molecular Biology 12 14%
Agricultural and Biological Sciences 11 13%
Neuroscience 7 8%
Pharmacology, Toxicology and Pharmaceutical Science 4 5%
Other 10 11%
Unknown 21 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 June 2015.
All research outputs
#6,271,351
of 22,754,104 outputs
Outputs from BMC Neuroscience
#298
of 1,242 outputs
Outputs of similar age
#60,058
of 227,083 outputs
Outputs of similar age from BMC Neuroscience
#5
of 29 outputs
Altmetric has tracked 22,754,104 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 1,242 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,083 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.