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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Mechanism of tumor rejection with doublets of CTLA-4, PD-1/PD-L1, or IDO blockade involves restored IL-2 production and proliferation of CD8+ T cells directly within the tumor microenvironment
|
|---|---|
| Published in |
Journal for Immunotherapy of Cancer, February 2014
|
| DOI | 10.1186/2051-1426-2-3 |
| Pubmed ID | |
| Authors |
Stefani Spranger, Holly K Koblish, Brendan Horton, Peggy A Scherle, Robert Newton, Thomas F Gajewski |
| Abstract |
Blockade of immune inhibitory pathways is emerging as an important therapeutic modality for the treatment of cancer. Single agent treatments have partial anti-tumor activity in preclinical models and in human cancer patients. Inasmuch as the tumor microenvironment shows evidence of multiple immune inhibitory mechanisms present concurrently, it has been reasoned that combination therapies may be required for optimal therapeutic effect. |
X Demographics
The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 33% |
| Russia | 1 | 11% |
| Mexico | 1 | 11% |
| Unknown | 4 | 44% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 44% |
| Practitioners (doctors, other healthcare professionals) | 3 | 33% |
| Scientists | 2 | 22% |
Mendeley readers
The data shown below were compiled from readership statistics for 470 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | <1% |
| Netherlands | 1 | <1% |
| Germany | 1 | <1% |
| France | 1 | <1% |
| Poland | 1 | <1% |
| Unknown | 462 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 117 | 25% |
| Student > Ph. D. Student | 87 | 19% |
| Student > Master | 40 | 9% |
| Student > Bachelor | 33 | 7% |
| Other | 31 | 7% |
| Other | 69 | 15% |
| Unknown | 93 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 93 | 20% |
| Medicine and Dentistry | 91 | 19% |
| Immunology and Microbiology | 62 | 13% |
| Biochemistry, Genetics and Molecular Biology | 60 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 19 | 4% |
| Other | 55 | 12% |
| Unknown | 90 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 23. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 April 2024.
All research outputs
#1,608,061
of 25,371,288 outputs
Outputs from Journal for Immunotherapy of Cancer
#409
of 3,421 outputs
Outputs of similar age
#15,985
of 238,829 outputs
Outputs of similar age from Journal for Immunotherapy of Cancer
#1
of 14 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,421 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.4. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 238,829 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.