Title |
A role for PAX8 in the tumorigenic phenotype of ovarian cancer cells
|
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Published in |
BMC Cancer, April 2014
|
DOI | 10.1186/1471-2407-14-292 |
Pubmed ID | |
Authors |
Tina Di Palma, Valeria Lucci, Tiziana de Cristofaro, Maria Grazia Filippone, Mariastella Zannini |
Abstract |
PAX8 is a member of the paired box (Pax) multigene family of transcription factors, which are involved in the developmental and tissue-specific control of the expression of several genes in both vertebrates and invertebrates. Previously, several studies reported that PAX8 is expressed at high levels in specific types of tumors. In particular, PAX8 has been recently reported to be conspicuously expressed in human ovarian cancer, but the functional role of PAX8 in the carcinogenesis of this type of tumor has not been addressed. In this study, we investigated the contribution of PAX8 in ovarian cancer progression. |
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Geographical breakdown
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Mexico | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 33% |
Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
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Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 7 | 15% |
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Other | 7 | 15% |
Unknown | 7 | 15% |
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