Title |
Tribbles expression in cumulus cells is related to oocyte maturation and fatty acid metabolism
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Published in |
Journal of Ovarian Research, April 2014
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DOI | 10.1186/1757-2215-7-44 |
Pubmed ID | |
Authors |
Daphné Brisard, Franck Chesnel, Sébastien Elis, Alice Desmarchais, Laura Sánchez-Lazo, Manon Chasles, Virginie Maillard, Svetlana Uzbekova |
Abstract |
In mammals, the Tribbles family includes widely expressed serine-threonine kinase-like proteins (TRIB1, TRIB2 and TRIB3) that are involved in multiple biological processes including cell proliferation and fatty acid (FA) metabolism. Our recent studies highlighted the importance of FA metabolism in cumulus cells (CC) during oocyte maturation in vertebrates and reported a higher TRIB1 expression in CC surrounding in vivo mature oocytes as compared to immature ooocytes in mice and cows. The objective was to investigate Tribbles expression patterns in bovine CC during in vitro maturation (IVM) and to examine their roles in the cumulus-oocyte complex. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 30 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 7 | 23% |
Student > Master | 5 | 17% |
Student > Doctoral Student | 4 | 13% |
Student > Bachelor | 3 | 10% |
Other | 3 | 10% |
Other | 7 | 23% |
Unknown | 1 | 3% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 16 | 53% |
Biochemistry, Genetics and Molecular Biology | 6 | 20% |
Medicine and Dentistry | 3 | 10% |
Philosophy | 1 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Other | 0 | 0% |
Unknown | 3 | 10% |