Title |
Predicting a local recurrence after breast-conserving therapy by gene expression profiling
|
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Published in |
Breast Cancer Research, October 2006
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DOI | 10.1186/bcr1614 |
Pubmed ID | |
Authors |
Dimitry SA Nuyten, Bas Kreike, Augustinus AM Hart, Jen-Tsan Ashley Chi, Julie B Sneddon, Lodewyk FA Wessels, Hans J Peterse, Harry Bartelink, Patrick O Brown, Howard Y Chang, Marc J van de Vijver |
Abstract |
To tailor local treatment in breast cancer patients there is a need for predicting ipsilateral recurrences after breast-conserving therapy. After adequate treatment (excision with free margins and radiotherapy), young age and incompletely excised extensive intraductal component are predictors for local recurrence, but many local recurrences can still not be predicted. Here we have used gene expression profiling by microarray analysis to identify gene expression profiles that can help to predict local recurrence in individual patients. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 1% |
France | 1 | 1% |
Unknown | 71 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 14 | 19% |
Researcher | 11 | 15% |
Student > Master | 7 | 10% |
Professor | 6 | 8% |
Professor > Associate Professor | 6 | 8% |
Other | 19 | 26% |
Unknown | 10 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 27 | 37% |
Agricultural and Biological Sciences | 12 | 16% |
Biochemistry, Genetics and Molecular Biology | 8 | 11% |
Computer Science | 4 | 5% |
Chemical Engineering | 2 | 3% |
Other | 7 | 10% |
Unknown | 13 | 18% |