Title |
Clinical and computed tomographic predictors of chronic bronchitis in COPD: a cross sectional analysis of the COPDGene study
|
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Published in |
Respiratory Research, April 2014
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DOI | 10.1186/1465-9921-15-52 |
Pubmed ID | |
Authors |
Victor Kim, Adam Davey, Alejandro P Comellas, Meilan K Han, George Washko, Carlos H Martinez, David Lynch, Jin Hwa Lee, Edwin K Silverman, James D Crapo, Barry J Make, Gerard J Criner, The COPDGene® Investigators |
Abstract |
Chronic bronchitis (CB) has been related to poor outcomes in Chronic Obstructive Pulmonary Disease (COPD). From a clinical standpoint, we have shown that subjects with CB in a group with moderate to severe airflow obstruction were younger, more likely to be current smokers, male, Caucasian, had worse health related quality of life, more dyspnea, and increased exacerbation history compared to those without CB. We sought to further refine our clinical characterization of chronic bronchitics in a larger cohort and analyze the CT correlates of CB in COPD subjects. We hypothesized that COPD patients with CB would have thicker airways and a greater history of smoking, acute bronchitis, allergic rhinitis, and occupational exposures compared to those without CB. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 2 | 50% |
United States | 1 | 25% |
Canada | 1 | 25% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 75% |
Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | <1% |
Unknown | 128 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 20 | 16% |
Student > Master | 18 | 14% |
Professor | 16 | 12% |
Student > Ph. D. Student | 11 | 9% |
Professor > Associate Professor | 8 | 6% |
Other | 30 | 23% |
Unknown | 26 | 20% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 61 | 47% |
Nursing and Health Professions | 9 | 7% |
Biochemistry, Genetics and Molecular Biology | 6 | 5% |
Immunology and Microbiology | 4 | 3% |
Agricultural and Biological Sciences | 3 | 2% |
Other | 16 | 12% |
Unknown | 30 | 23% |