Title |
Immune-modulatory effects of dietary Yeast Beta-1,3/1,6-D-glucan
|
---|---|
Published in |
Nutrition Journal, April 2014
|
DOI | 10.1186/1475-2891-13-38 |
Pubmed ID | |
Authors |
Heike Stier, Veronika Ebbeskotte, Joerg Gruenwald |
Abstract |
Beta-glucans are a heterogeneous group of natural polysaccharides mostly investigated for their immunological effects. Due to the low systemic availability of oral preparations, it has been thought that only parenterally applied beta-glucans can modulate the immune system. However, several in vivo and in vitro investigations have revealed that orally applied beta-glucans also exert such effects. Various receptor interactions, explaining possible mode of actions, have been detected. The effects mainly depend on the source and structure of the beta-glucans. In the meantime, several human clinical trials with dietary insoluble yeast beta-glucans have been performed. The results confirm the previous findings of in vivo studies. The results of all studies taken together clearly indicate that oral intake of insoluble yeast beta-glucans is safe and has an immune strengthening effect. |
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India | 1 | 5% |
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Unknown | 6 | 30% |
Demographic breakdown
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Practitioners (doctors, other healthcare professionals) | 6 | 30% |
Scientists | 4 | 20% |
Science communicators (journalists, bloggers, editors) | 1 | 5% |
Mendeley readers
Geographical breakdown
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Australia | 1 | <1% |
Brazil | 1 | <1% |
Belgium | 1 | <1% |
Spain | 1 | <1% |
Greece | 1 | <1% |
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Researcher | 45 | 13% |
Student > Bachelor | 41 | 11% |
Student > Ph. D. Student | 39 | 11% |
Student > Doctoral Student | 26 | 7% |
Other | 69 | 19% |
Unknown | 79 | 22% |
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Immunology and Microbiology | 17 | 5% |
Other | 69 | 19% |
Unknown | 93 | 26% |