Title |
Diagnosis of periarticular osteoporosis in rheumatoid arthritis using digital X-ray radiogrammetry
|
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Published in |
Arthritis Research & Therapy, January 2008
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DOI | 10.1186/ar2352 |
Pubmed ID | |
Authors |
Joachim Böttcher, Alexander Pfeil |
Abstract |
Osteoporosis can manifest in two ways in rheumatoid arthritis: generalized bone loss, which may result from immobility, the inflammatory process per se and/or treatments such as steroids; and periarticular demineralization, which is probably due to local release of inflammatory agents. Digital X-ray radiogrammetry (DXR) is an effective and sensitive modality for monitoring periarticular osteoporosis, which is among the earliest features of rheumatoid arthritis, preceding bone erosions. DXR is a promising technique, which can provide quantitative data that allow early diagnosis. During the course of rheumatoid arthritis it can be deployed in combination with established X-ray scoring methods to inform decisions regarding the optimal therapy to prevent joint destruction. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Finland | 1 | 4% |
Spain | 1 | 4% |
Unknown | 24 | 92% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 4 | 15% |
Student > Bachelor | 3 | 12% |
Researcher | 3 | 12% |
Student > Ph. D. Student | 3 | 12% |
Student > Doctoral Student | 2 | 8% |
Other | 6 | 23% |
Unknown | 5 | 19% |
Readers by discipline | Count | As % |
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Physics and Astronomy | 1 | 4% |
Other | 3 | 12% |
Unknown | 5 | 19% |