Title |
MetaSel: a metaphase selection tool using a Gaussian-based classification technique
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Published in |
BMC Bioinformatics, October 2013
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DOI | 10.1186/1471-2105-14-s16-s13 |
Pubmed ID | |
Authors |
Ravi Uttamatanin, Peerapol Yuvapoositanon, Apichart Intarapanich, Saowaluck Kaewkamnerd, Ratsapan Phuksaritanon, Anunchai Assawamakin, Sissades Tongsima |
Abstract |
Identification of good metaphase spreads is an important step in chromosome analysis for identifying individuals with genetic disorders. The process of finding suitable metaphase chromosomes for accurate clinical analysis is, however, very time consuming since they are selected manually. The selection of suitable metaphase chromosome spreads thus represents a major bottleneck for conventional cytogenetic analysis. Although many algorithms have been developed for karyotyping, none have adequately addressed the critical bottleneck of selecting suitable chromosome spreads. In this paper, we present a software tool that uses a simple rule-based system to efficiently identify metaphase spreads suitable for karyotyping. |
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Unknown | 2 | 100% |
Demographic breakdown
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Scientists | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 26 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 6 | 23% |
Student > Master | 4 | 15% |
Student > Ph. D. Student | 3 | 12% |
Student > Doctoral Student | 2 | 8% |
Other | 1 | 4% |
Other | 5 | 19% |
Unknown | 5 | 19% |
Readers by discipline | Count | As % |
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Engineering | 7 | 27% |
Agricultural and Biological Sciences | 5 | 19% |
Computer Science | 4 | 15% |
Biochemistry, Genetics and Molecular Biology | 3 | 12% |
Medicine and Dentistry | 1 | 4% |
Other | 1 | 4% |
Unknown | 5 | 19% |