Title |
The SystHERs registry: an observational cohort study of treatment patterns and outcomes in patients with human epidermal growth factor receptor 2–positive metastatic breast cancer
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Published in |
BMC Cancer, May 2014
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DOI | 10.1186/1471-2407-14-307 |
Pubmed ID | |
Authors |
Debu Tripathy, Hope S Rugo, Peter A Kaufman, Sandra Swain, Joyce O’Shaughnessy, Mohammad Jahanzeb, Ginny Mason, Mary Beattie, Bongin Yoo, Catherine Lai, Anthony Masaquel, Sara Hurvitz |
Abstract |
Amplification of the human epidermal growth factor receptor 2 (HER2) gene occurs in approximately 20% of invasive breast cancer cases and is associated with a more aggressive disease course than HER2-negative breast cancer. HER2-targeted therapies have altered the natural history of HER2-positive breast cancer, a trend that will likely further improve with the recent approval of new agents. A prospective, observational cohort study was designed and initiated to provide real-world insights into current treatment patterns, long-term survival, and patients' experiences with initial and subsequent treatments for HER2-positive metastatic breast cancer (MBC). |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 1% |
France | 1 | 1% |
Unknown | 85 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 15 | 17% |
Student > Master | 12 | 14% |
Other | 8 | 9% |
Student > Bachelor | 8 | 9% |
Student > Postgraduate | 7 | 8% |
Other | 18 | 21% |
Unknown | 19 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 27 | 31% |
Nursing and Health Professions | 8 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 7 | 8% |
Economics, Econometrics and Finance | 4 | 5% |
Psychology | 3 | 3% |
Other | 11 | 13% |
Unknown | 27 | 31% |