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The epigenetic effects of butyrate: potential therapeutic implications for clinical practice

Overview of attention for article published in Clinical Epigenetics, February 2012
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

Mentioned by

news
2 news outlets
twitter
28 X users
facebook
3 Facebook pages
reddit
1 Redditor

Citations

dimensions_citation
315 Dimensions

Readers on

mendeley
332 Mendeley
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Title
The epigenetic effects of butyrate: potential therapeutic implications for clinical practice
Published in
Clinical Epigenetics, February 2012
DOI 10.1186/1868-7083-4-4
Pubmed ID
Authors

Roberto Berni Canani, Margherita Di Costanzo, Ludovica Leone

Abstract

Butyrate is a short chain fatty acid derived from the microbial fermentation of dietary fibers in the colon. In the last decade, multiple beneficial effects of butyrate at intestinal and extraintestinal level have been demonstrated. The mechanisms of action of butyrate are different and many of these involve an epigenetic regulation of gene expression through the inhibition of histone deacetylase. There is a growing interest in butyrate because its impact on epigenetic mechanisms will lead to more specific and efficacious therapeutic strategies for the prevention and treatment of different diseases ranging from genetic/metabolic conditions to neurological degenerative disorders. This review is focused on recent data regarding the epigenetic effects of butyrate with potential clinical implications in human medicine.

X Demographics

X Demographics

The data shown below were collected from the profiles of 28 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 332 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 1%
Germany 2 <1%
Australia 1 <1%
Portugal 1 <1%
United Kingdom 1 <1%
South Africa 1 <1%
Estonia 1 <1%
Slovenia 1 <1%
Unknown 320 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 47 14%
Student > Master 42 13%
Student > Bachelor 39 12%
Researcher 38 11%
Student > Doctoral Student 19 6%
Other 56 17%
Unknown 91 27%
Readers by discipline Count As %
Agricultural and Biological Sciences 68 20%
Biochemistry, Genetics and Molecular Biology 60 18%
Medicine and Dentistry 56 17%
Immunology and Microbiology 11 3%
Nursing and Health Professions 10 3%
Other 32 10%
Unknown 95 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 37. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 December 2023.
All research outputs
#1,097,269
of 25,483,400 outputs
Outputs from Clinical Epigenetics
#54
of 1,438 outputs
Outputs of similar age
#5,280
of 168,281 outputs
Outputs of similar age from Clinical Epigenetics
#2
of 6 outputs
Altmetric has tracked 25,483,400 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,438 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 168,281 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.