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The epigenetic effects of butyrate: potential therapeutic implications for clinical practice

Overview of attention for article published in Clinical Epigenetics, January 2012
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#25 of 946)
  • High Attention Score compared to outputs of the same age (95th percentile)

Mentioned by

news
2 news outlets
twitter
23 tweeters
facebook
3 Facebook pages
reddit
1 Redditor

Citations

dimensions_citation
205 Dimensions

Readers on

mendeley
250 Mendeley
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Title
The epigenetic effects of butyrate: potential therapeutic implications for clinical practice
Published in
Clinical Epigenetics, January 2012
DOI 10.1186/1868-7083-4-4
Pubmed ID
Authors

Roberto Berni Canani, Margherita Di Costanzo, Ludovica Leone

Abstract

Butyrate is a short chain fatty acid derived from the microbial fermentation of dietary fibers in the colon. In the last decade, multiple beneficial effects of butyrate at intestinal and extraintestinal level have been demonstrated. The mechanisms of action of butyrate are different and many of these involve an epigenetic regulation of gene expression through the inhibition of histone deacetylase. There is a growing interest in butyrate because its impact on epigenetic mechanisms will lead to more specific and efficacious therapeutic strategies for the prevention and treatment of different diseases ranging from genetic/metabolic conditions to neurological degenerative disorders. This review is focused on recent data regarding the epigenetic effects of butyrate with potential clinical implications in human medicine.

Twitter Demographics

The data shown below were collected from the profiles of 23 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 250 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 2%
Germany 2 <1%
South Africa 1 <1%
Australia 1 <1%
United Kingdom 1 <1%
Slovenia 1 <1%
Estonia 1 <1%
Portugal 1 <1%
Unknown 238 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 46 18%
Student > Master 37 15%
Student > Bachelor 35 14%
Researcher 33 13%
Student > Doctoral Student 18 7%
Other 44 18%
Unknown 37 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 60 24%
Biochemistry, Genetics and Molecular Biology 54 22%
Medicine and Dentistry 45 18%
Immunology and Microbiology 10 4%
Nursing and Health Professions 9 4%
Other 29 12%
Unknown 43 17%

Attention Score in Context

This research output has an Altmetric Attention Score of 35. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 April 2021.
All research outputs
#710,613
of 17,464,602 outputs
Outputs from Clinical Epigenetics
#25
of 946 outputs
Outputs of similar age
#8,922
of 197,239 outputs
Outputs of similar age from Clinical Epigenetics
#1
of 1 outputs
Altmetric has tracked 17,464,602 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 946 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.1. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 197,239 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them